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032 Time to reperfusion does not predict clinical outcomes in anterior circulation stroke patients undergoing thrombectomy within 8 h of symptoms onset: pooled analysis of the Merci and Multimerci trials
  1. R Nogueira,
  2. W Smith,
  3. G Duckwiler,
  4. G Sung,
  5. D Liebeskind
  1. 1Interventional Neuroradiology and Endovascular Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts, USA
  2. 2Neurology, University of California San Francisco, San Francisco, California, USA
  3. 3Interventional Neuroradiology, University of California, Los Angeles, Los Angeles, California, USA
  4. 4Neurology, University of Southern California, Los Angeles, California, USA
  5. 5Interventional Neuroradiology and Endovascular Neurosurgery, University of California, Los Angeles, Los Angeles, California, USA

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Background and Purpose: The Merci and Multi-Merci trials evaluated the safety and efficacy of endovascular thrombectomy with the Merci Retriever in the treatment of proximal intracranial arterial occlusions performed within 8 h of stroke symptom onset. We sought to determine whether time to reperfusion influences clinical outcomes in the context of anterior circulation thrombectomy. In addition, we investigated which baseline factors predict good clinical outcomes and mortality in successfully revascularized anterior circulation occlusion patients.

Methods: The subjects of this study included all patients in the Merci/Multi-Merci studies who presented with occlusion involving the intracranial internal carotid artery (ICA) and/or the proximal middle cerebral artery (MCA) (M1–M2 segments) and were successfully revascularized (post-Retriever/post-adjunctive TIMI 2–3 …

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