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Letter to the editor
Caution during use of desmopressin in IPSS
  1. Amy R Deipolyi1,
  2. Joshua A Hirsch2,
  3. Rahmi Oklu1
  1. 1Vascular Imaging and Interventions, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
  2. 2Neurointerventional Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA
  1. Correspondence to Rahmi Oklu, Vascular Imaging and Interventions, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, GRB-290A, Boston, MA 02114, USA; rahmioklu{at}gmail.com

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We thank Dr Pecori Giraldi and colleagues for their letter concerning caution during the use of desmopressin in inferior petrosal sinus sampling (IPSS). The authors suggest that, because of the hypercoagulable state that characterizes Cushing's disease, desmopressin may not be safe since it has been shown to increase the level of von Willebrand factor and could therefore lead …

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