Introduction CT perfusion imaging is commonly used in evaluation of patients who present with symptoms of acute ischemic stroke. Numerous entities can simulate an acute cerebral infarct. Knowledge of the common imaging manifestations of non- ischemic entities can prevent misdiagnosis and can facilitate appropriate therapy. We present a review of findings of common non-ischemic entities on CT perfusion imaging.

Materials and methods We present several cases of non-ischemic diagnosis and review their imaging findings on CTP. This includes: malignancy, Todd’s paralysis, Multiple Sclerosis, migraine headaches, Bell’s palsy, complex seizure disorder, hypertensive encephalopathy, herpes encephalitis and chronic subdural hematoma.

Conclusion The radiologist should be aware of the imaging findings of etiologies which may mimic an acute ischemic stroke on CT perfusion imaging.

Disclosures M. Chehab: None. J. Wilseck: None.