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Original research
Comaneci neck bridging device for the treatment of cerebral aneurysms
  1. Rishi Gupta1,
  2. Frank D Kolodgie2,
  3. Renu Virmani2,
  4. Ronen Eckhouse3
  1. 1Wellstar Medical Group Neurosurgery, Wellstar Neurosciences Network, Marietta, Georgia, USA
  2. 2Department of Cardiology, CVPath Institute, Gaithersburg, Maryland, USA
  3. 3Rapid Medical, Yokneam, Israel
  1. Correspondence to Dr Rishi Gupta, Wellstar Medical Group, Neurosurgery, 61 Whitcher Street, Suite 3110, Marietta, GA 30060, USA; rishi.gupta{at}wellstar.org

Abstract

Background and purpose Adjunctive devices are commonly employed in the treatment of wide necked cerebral aneurysms. Balloon remodeling and permanent stent implantation may lead to thromboembolic complications or the need for antiplatelet use. A temporary stent that does not lead to complete flow arrest may be beneficial.

Methods We studied 20 New Zealand white rabbits in whom aneurysms were created using elastase and ligation of the right common carotid artery. The aneurysms were then embolized with bare platinum coils along with adjunctive treatment using the Comaneci device or the Hyperglide balloon. Assessments were made for endothelial injury using scanning electron microscopy (SEM) and light microscopy.

Results 20 rabbits of mean±SD weight 3.1±0.2 kg were studied. Twelve rabbits were treated with the Comaneci device and eight with the Hyperglide balloon. There were no substantial differences on SEM or light microscopy in the subacute and chronic phase to suggest the Comaneci device caused endothelial injury.

Conclusions The Comaneci device is a new adjuvant treatment for bridging of wide necked aneurysms with the advantage of averting flow arrest during deployment. There does not appear to be any evidence of significant endothelial damage during deployment in preclinical studies.

  • Aneurysm
  • Stent
  • Device

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