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O-014 Vision Outcomes for Paraclinoid Aneurysms Treated with Flow Diverters
  1. M Silva,
  2. A See,
  3. H Dasenbrock,
  4. P Khandelwal,
  5. N Patel,
  6. M Aziz-Sultan
  1. Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA

Abstract

Introduction Aneurysms of the paraclinoid region of the internal carotid artery (ICA) and the interventions used to treat them often result in visual impairment. Because of the proximity of these aneurysms to the optic nerve and the ophthalmic artery, between 16% and 53% of patients present with visual deficits. While flow diversion is increasingly used throughout endovascular neurosurgery, few studies have reported the visual outcomes of treating paraclinoid aneurysms with this technique or compared it to coiling or clipping.

Hypothesis In order to satisfy demand for data on the visual outcomes for this new endovascular treatment modality and inform the contemporary management of paraclinoid aneurysms, we performed a retrospective analysis of patients with paraclinoid aneurysms treated at our site with a Pipeline embolization device (PED).

Methods We compiled visual outcome data for 20 patients presenting with 26 paraclinoid aneurysms and treated at our site with flow diversion, 10 of whom (totaling 13 aneurysms) presented with visual impairment. We then reviewed vision outcomes in these patients at discharge and at 6 months, noting improved, unchanged, deteriorated, or newly impaired vision. We also performed an extensive literature review to compile data (1447 cases from 21 sites) on vision outcomes for paraclinoid aneurysms treated with clips (534 cases), coils (638), or flow diverters (275).

Results Of twenty patients with 26 paraclinoid aneurysms treated at our site with a PED, ten patients (totaling 13 aneurysms with an average diameter of 7.1 mm) presented with preoperative visual impairment. Visual deficits were improved in 8 patients (80%) and unchanged in 2 (20%) following treatment. No patients experienced sustained worsening of their existing visual impairment, however one patient acquired postoperative iatrogenic vision impairment (5%). A literature review of paraclinoid aneurysm treatment revealed visual improvement rates of approximately 41% for clipping, 54% for coiling, and 73% for flow diversion, visual deterioration rates of approximately 14%, 23%, and 2%, and newly impaired vision rates of 9%, 3%, and 4%.

Conclusion Compared to clipping and coiling, flow diversion demonstrates a higher rate of visual improvement and a lower rate of visual decline in patients with visually symptomatic paraclinoid aneurysms, with comparable risk of iatrogenic vision impairment. We report strong visual outcomes in patients treated at our site for paraclinoid aneurysms with a PED, including small aneurysms. Our results suggest that this new treatment modality yields improved vision outcomes in patients with paraclinoid aneurysms compared to clipping and coiling.

Abstract O-014 Table 1

Disclosures M. Silva: None. A. See: None. H. Dasenbrock: None. P. Khandelwal: None. N. Patel: None. M. Aziz-Sultan: 2; C; Covidien.

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work noncommercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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