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Letter to the Editor
Midnight in the Garden of Yea or Nay
  1. Bharathi D Jagadeesan
  1. Correspondence to Dr Bharathi D Jagadeesan, Radiology, Neurosurgery and Neurology, University of Minnesota, Minneapolis, MN 55455, USA; jagad002{at}umn.edu

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A year or so ago, the Interventional Management of Stroke III (IMS III) trial had burst upon the world of endovascular surgical neuroradiology specialists as a level one ‘Nay’, and as a group we were left wondering, are we even making a difference? As one of the last generation of interventional neuroradiologists, a species somewhat akin to Daenerys Targaryen’s dragons, I was able to watch with concern and consternation as several editorials by my peers and others trashed endovascular stroke treatment and found comfort in ‘we told you so’ moments. I also witnessed several patients being denied treatment based on evidence from IMS III. It looked as though we had entered a long night of hopelessness.

More importantly, many of our patients were facing this time of darkness. Editorials in shades of regressive nihilism such as “death and destruction in …

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