Article Text

other Versions

PDF
Original research
Occurrence of angiographic femoral artery complications after vascular closure with Mynx and AngioSeal
  1. Kyle M Fargen1,
  2. Gregory J Velat1,
  3. Matthew F Lawson1,
  4. Charles A Ritchie2,
  5. Christopher Firment2,
  6. Brian L Hoh1,
  7. Jeffery A Bennett2,
  8. J Mocco3
  1. 1Department of Neurosurgery, University of Florida, Gainesville, Florida, USA
  2. 2Department of Radiology, University of Florida, Gainesville, Florida, USA
  3. 3Department of Neurosurgery, Vanderbilt University, Nashville, Tennessee, USA
  1. Correspondence to Dr Kyle Michael Fargen, Department of Neurosurgery, University of Florida, Box 100265, Gainesville, FL 32610, USA; kyle.fargen{at}neurosurgery.ufl.edu

Abstract

Introduction There have been recent reports of high vascular complication rates after the use of the Mynx vascular closure device (VCD). At our institution, vascular complications due to these devices have rarely been encountered. A study was undertaken to retrospectively compare angiographic abnormalities seen after femoral artery closure by both the Mynx and AngioSeal VCDs to provide further insight into the risks associated with VCDs.

Methods All adult patients who underwent deployment of either a Mynx or AngioSeal VCD and subsequently underwent repeat angiography within the next 30 days between 1 July 2010 and 1 April 2011 were reviewed. Two independent blinded radiologists compared blinded pre-procedure and follow-up femoral angiograms for the presence of pseudoaneurysm or other vascular abnormality. Hospital records were reviewed for major or minor complications of the groin site or femoral artery.

Results Thirty patients (31 angiograms) underwent vascular closure with a Mynx and 57 patients (69 angiograms) received an AngioSeal. The average time elapse until repeat femoral angiography was 6.2 days (range 1–21, median 5.5 days) in the Mynx group and 6.3 days (range 0–30, median 5 days) in the AngioSeal group. Two pseudoaneurysms and one minor stenosis were identified in the AngioSeal group. No angiographic abnormalities were seen in the Mynx group. No intraluminal filling defects were demonstrated on any of the follow-up femoral angiograms. One patient who received an AngioSeal developed a delayed minor groin site hematoma that did not require surgical intervention.

Conclusions Angiographic complications were seen in only 3% of patients after closure with Mynx or AngioSeal VCDs. There were no clinically significant groin site or vascular complications. These data suggest that both VCDs are safe for use after angiography with a low rate of femoral artery complications.

  • Angiography
  • cerebrovascular
  • femoral artery
  • vascular closure device
  • aneurysm
  • artery
  • spinal cord
  • subarachnoid
  • thrombectomy
  • catheter
  • neck
  • navigation

Statistics from Altmetric.com

Footnotes

  • Funding No funding was obtained for the completion of this manuscript. One-time non-monetary grant support had previously been received from Access Closure Inc (more than 2 years previously) for a different study.

  • Competing interests None.

  • Ethics approval Ethics approval was provided by University of Florida IRB.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.