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We thank Coutinho et al1 for their comments on our manuscript. They state that the 4% mortality associated with non-invasive anticoagulant treatment in the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) is superior to our observed mortality rate of 15% (two of 13 patients). The ISCVT is a large prospective trial, which is detailed in the discussion section of our article. A direct comparison of mortality rates between …
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