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Original research
Novel aneurysm neck reconstruction device: initial experience in an experimental preclinical bifurcation aneurysm model
  1. Aquilla Turk1,
  2. Raymond D Turner2,
  3. Satoshi Tateshima3,
  4. David Fiorella4,
  5. Kyung-Sool Jang5,
  6. Imran Chaudry1,
  7. Michael Kelly6
  1. 1Department of Radiology, Stroke and Cerebrovascular Center, Medical University of South Carolina, Charleston, South Carolina, USA
  2. 2Department of Neurosciences, Stroke and Cerebrovascular Center, Medical University of South Carolina, Charleston, South Carolina, USA
  3. 3Division of Interventional Neuroradiology, Department of Radiological Sciences, Ronald Reagan UCLA Medical Center, Los Angeles, California, USA
  4. 4Department of Neurological Surgery, Stony Brook University Medical Center, Stony Brook, New York, USA
  5. 5Department of Neurosurgery, Stroke and Cerebrovascular Center, The Catholic University of Korea, Incheon, Korea
  6. 6Division of Neurosurgery, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan
  1. Correspondence to Dr Aquilla Turk, Stroke and Cerebrovascular Center, Department of Radiology, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 337F CSB, Charleston, SC 29466, USA; turk{at}musc.edu

Abstract

Introduction Treatment of wide-necked bifurcation aneurysms often poses procedural and long-term outcome challenges. The initial preclinical experience with the Pulsar Vascular Aneurysm Neck Reconstruction Device (PVANRD) in a canine bifurcation model is described.

Methods Experimental bifurcation vein pouch aneurysms were surgically created in the carotid arteries of eight dogs. Endovascular coiling of the aneurysms with assistance of the PVANRD was performed in all cases with acute performance compared with Y-stenting.

Results Twelve devices were deployed in the eight cases. Deployment of the devices was straightforward and successfully protected the parent artery and maintained patency of the bifurcation in all cases, despite the use of oversized coils.

Conclusion The PVANRD is a novel bifurcation stent that facilitates treatment of wide-necked bifurcation aneurysms compared with currently available adjunctive devices.

  • Aneurysm
  • wide-necked
  • reconstruction
  • device
  • stent
  • artery
  • MRI
  • CT
  • vein
  • thrombectomy
  • spine
  • subarachnoid
  • coil
  • angioplasty
  • arteriovenous malformation
  • flow diverter
  • spinal cord
  • navigation
  • complication
  • balloon
  • thrombolysis
  • stroke

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Footnotes

  • Contributors Each author listed should receive authorship credit based on their material contribution to this article, their revision of this article, and their final approval of this article for submission to this journal.

  • Funding This work was supported by Pulsar Vascular Inc (grant number 88183).

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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