Article Text

other Versions

PDF
Original research
Association of aneurysms and variation of the A1 segment
  1. A Krasny1,
  2. F Nensa1,
  3. I E Sandalcioglu2,
  4. S L Göricke1,
  5. I Wanke1,
  6. C Gramsch1,
  7. S Sirin1,
  8. N Oezkan2,
  9. U Sure2,
  10. M Schlamann1
  1. 1Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany
  2. 2Department of Neurosurgery, University Hospital Essen, Essen, Germany
  1. Correspondence to Dr A Krasny, Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Hufelandstraße 55, Essen D-45122, Germany; andrej.krasny{at}uk-essen.de

Abstract

Background and purpose Previous studies have described a correlation between variants of the circle of Willis and pathological findings, such as cerebrovascular diseases. Moreover, anatomic variations of the anterior cerebral artery (ACA) seem to correspond to the prevalence of aneurysms in the anterior communicating artery (ACoA). The aim of this study was to assess the prevalence of aneurysms in patients with anatomical/morphological variations of the circle of Willis.

Methods We retrospectively analyzed 223 patients who underwent cerebral angiography between January 2002 and December 2010 for aneurysm of the ACoA. Diagnostic imaging was reviewed and statistically evaluated to detect circle of Willis anomalies, aneurysm size, and rupture. 204 patients with an unrelated diagnosis served as the control group.

Results Variations of the A1 segment occurred significantly more frequently in the aneurysm group than in the control group. Mean aneurysm size in patients with grades I and III hypoplasia or aplasia was 6.58 mm whereas in patients with grade II hypoplasia it was 7.76 mm.

Conclusions We found that variations in the A1 segment of the ACAs are correlated with a higher prevalence of ACoA aneurysms compared with patients with a symmetric circle of Willis.

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.