Article Text

other Versions

PDF
Original research
Computational fluid dynamics with stents: quantitative comparison with particle image velocimetry for three commercial off the shelf intracranial stents
  1. Pierre Bouillot1,2,
  2. Olivier Brina1,
  3. Rafik Ouared1,
  4. Hasan Yilmaz1,
  5. Karl-Olof Lovblad1,
  6. Mohamed Farhat2,
  7. Vitor Mendes Pereira1,3,4
  1. 1Interventional Neuroradiology Unit, Service of Neuroradiology, University Hospitals of Geneva, Geneva, Switzerland
  2. 2Laboratory for Hydraulic Machines (LMH), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland
  3. 3Division of Neuroradiology, Department of Medical Imaging, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
  4. 4Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
  1. Correspondence to Dr V Mendes Pereira, Division of Neuroradiology, Department of Medical Imaging and Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, University Health Network, 3MCL-436, 399 Bathurst St, Toronto, Ontario, Canada M5T 2S8; vitormpbr{at}hotmail.com

Abstract

Background and purpose Validation of computational fluid dynamics (CFD) in stented intracranial aneurysms (IAs) is still lacking, to reliably predict prone to occlusion hemodynamics, probing, in particular, velocity reduction, and flow pattern changes. This study compares CFD outcome with particle imaging velocimetry (PIV) for three commercial off the shelf (COTS) stents of different material densities.

Material and methods The recently developed uniform and high precision multi-time lag PIV method was applied to a sidewall aneurysm before and after implantation of three COTS stents with high, intermediate, and low material densities. The measured laser sheet flow patterns and velocity reductions were compared with CFD results and correlated with stent material density.

Results Velocity reduction was in good agreement for unstented high and low porosity stented IA, while flow pattern change was fully matched for unstented and high porosity stented IA. Poor CFD–PIV matching in IA was found for intermediate porosity stents.

Conclusions CFD reproduced fully PIV measurements in unstented and high porosity stented IAs. With low porosity stents, CFD reproduced velocity reduction and high velocities close to the neck, while a marked mismatch on sluggish flow was found at the dome. CFD was unable to match PIV with intermediate porosity stents for which hemodynamic transition occurred.

  • Aneurysm
  • Blood Flow
  • Flow Diverter
  • Technology

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.