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Letter to the Editor
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  1. Maxim Mokin1,5,
  2. Simon Morr1,5,
  3. Sabareesh K Natarajan1,5,
  4. Ning Lin1,5,
  5. Kenneth V Snyder1,2,3,4,5,
  6. L Nelson Hopkins1,3,4,5,6,
  7. Adnan H Siddiqui1,3,4,5,6,
  8. Elad I Levy1,3,4,5
  1. 1Department of Neurosurgery, University at Buffalo, State University of New York, Buffalo, New York, USA
  2. 2Department of Neurology, University at Buffalo, State University of New York, Buffalo, New York, USA
  3. 3Department Radiology, University at Buffalo, State University of New York, Buffalo, New York, USA
  4. 4Toshiba Stroke and Vascular Research Center, University at Buffalo, State University of New York, Buffalo, New York, USA
  5. 5Department of Neurosurgery, Gates Vascular Institute and Kaleida Health, Buffalo, New York, USA
  6. 6Jacobs Institute, Buffalo, New York, USA
  1. Correspondence to Dr Elad I Levy, Department of Neurosurgery, University at Buffalo, State University of New York, Buffalo, NY 14203, USA; ELevy{at}ubns.com

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We thank the authors for their interest in our article.1 We also believe that the combined IV thrombolysis plus stent retriever thrombectomy approach might show a different association between thrombus density and recanalization outcomes than stent retriever thrombectomy alone, which was the focus of our paper. These two distinct groups of patients (thrombectomy with or without preceding administration of IV recombinant tissue plasminogen activator (rtPA)) should be studied separately, as both treatments are now widely applied to modern practice.

We argue that IA administration of rtPA during IA thrombectomy is rather uncommon. For example, early postmarket experience with the Solitaire FR device …

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