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Neuroimaging
Original research
Wall enhancement ratio and partial wall enhancement on MRI associated with the rupture of intracranial aneurysms
  1. Guang-xian Wang1,
  2. Li Wen1,
  3. Sheng Lei1,
  4. Qian Ran1,
  5. Jin-bo Yin2,
  6. Zi-li Gong3,
  7. Dong Zhang1
  1. 1Department of Radiology, Xinqiao Hospital, Third Military Medical University, Chongqing, China
  2. 2Department of Neurosurgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
  3. 3Department of Neurology, Xinqiao Hospital, Third Military Medical University, Chongqing, China
  1. Correspondence to Dr Dong Zhang, Department of Radiology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China; xqzhangdong{at}163.com

Abstract

Objectives To evaluate the risk factors for rupture of intracranial aneurysms (IAs) using high resolution MRI (HRMRI).

Methods 91 consecutive patients with 106 IAs were reviewed from February 2016 to April 2017. Patients and IAs were divided into ruptured and unruptured groups. In addition to the clinical characteristics of the patients, the features of IAs (eg, shape) were evaluated by CT angiography, whereas wall thickness, enhanced patterns, and enhancement ratio (ER) were evaluated by MRI. Multiple logistic regression analysis was used to identify independent risk factors associated with the rupture of IAs. Receiver operating characteristic curve analysis was performed on the final model, and the optimal thresholds were obtained.

Results ER (OR 6.638) and partial wall enhancement (PWE) (OR 6.710) were not markers of aneurysms more prone to rupture, but simply were more commonly found in the ruptured aneurysm cohort. The threshold value for ER was 61.5%.

Conclusions ER (≥61.5%) and IAs with PWE are better predictors of rupture. Increased attentions should be paid to these factors during assessment of IA rupture.

  • intracranial aneurysm
  • magnetic resonance imaging
  • rupture
  • risk factors
  • enhancement ratio

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

https://doi.org/10.1136/neurintsurg-2017-013308

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    Footnotes

    • Contributors Conceptualization: DZ. Data curation: LW. Investigation: SL, QR, J-bY, Z-lG. Methodology: DZ. Writing original draft: G-xW.

    • Funding The study was supported by the Research Project of the Third Military Medical University (2016YLC22).

    • Competing interests None declared.

    • Patient consent Obtained.

    • Ethics approval The study was approved by our institutional ethics committee (Xinqiao Hospital, 2016031).

    • Provenance and peer review Not commissioned; externally peer reviewed.