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Mechanical thrombectomy of acute ischemic stroke with a new intermediate aspiration catheter: preliminary results

Abstract

Background and purpose To report clinical and procedural outcomes of acute ischemic stroke patients after endovascular treatment with the new thromboaspiration catheter AXS Catalyst 6.

Methods Patients with anterior and posterior circulation stroke were selected. Successful reperfusion defined as a Thrombolysis in Cerebral Infarction (TICI) score ≥2 b and 3-month functional independence defined as a modified Rankin Scale (mRS) ≤2 were the main efficacy outcomes. Symptomatic intracranial hemorrhage and mortality were the main safety outcomes.

Results 107 patients were suitable for analysis. Mean age was 73.18±12.62 year and median baseline NIHSS was 17 (range: 3–32). The most frequent site of occlusion was the middle cerebral artery (MCA) (60.7%). 76.6% of patients were treated with AXS Catalyst 6 alone without the need for rescue devices or thromboaspiration catheters. Successful reperfusion was achieved in 84.1%, functional independence in 47.6%, symptomatic intracranial hemorrhage occurred in 3.7%, and mortality in 21.4%.

Conclusions Endovascular treatment with AXS Catalyst 6 proved to be safe, technically feasible, and effective. Comparison analyses with other devices for mechanical thrombectomy are needed.

  • catheter
  • device
  • stroke
  • thrombectomy

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Footnotes

  • Contributors FS: conception of the work, acquisition and interpretation of data; drafting the work; final approval; accountable for all aspects. EP: design of the work; drafting the work; revising the work for important intellectual content; final approval; accountable for all aspects. AD: acquisition and analysis of data; drafting the work; final approval; accountable for all aspects. SM: conception of the work, acquisition and interpretation of data; final approval; accountable for all aspects. GK: acquisition and interpretation of data; revising the work; final approval; accountable for all aspects. FA: acquisition and interpretation of data; revising the work; final approval; accountable for all aspects. MP: acquisition and interpretation of data; revising the work; final approval; accountable for all aspects. VCA: acquisition and interpretation of data; revising the work; final approval; accountable for all aspects. FM: acquisition and interpretation of data; revising the work; final approval; accountable for all aspects. DM: acquisition and interpretation of data; revising the work; final approval; accountable for all aspects. DK: acquisition and interpretation of data; revising the work; final approval; accountable for all aspects. SF: acquisition and interpretation of data; revising the work; final approval; accountable for all aspects. MD: conception of the work, interpretation of data; revising the work for important intellectual content; final approval; accountable for all aspects. RG: design of the work; analysis and interpretation of data; revising the work for important intellectual content; final approval; accountable for all aspects.

  • Funding This work was supported by the Italian Ministry of Health (RF-2013-02358679).

  • Competing interests None declared.

  • Patient consent Obtained.

  • Ethics approval Local Ethics Committee.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement Reasearch data will be available for sharing on request in the respect of Local Ethic Committee rules.

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