RT Journal Article
SR Electronic
T1 Wall enhancement ratio and partial wall enhancement on MRI associated with the rupture of intracranial aneurysms
JF Journal of NeuroInterventional Surgery
JO J NeuroIntervent Surg
FD BMJ Publishing Group Ltd.
SP neurintsurg-2017-013308
DO 10.1136/neurintsurg-2017-013308
A1 Guang-xian Wang
A1 Li Wen
A1 Sheng Lei
A1 Qian Ran
A1 Jin-bo Yin
A1 Zi-li Gong
A1 Dong Zhang
YR 2017
UL http://jnis.bmj.com/content/early/2017/09/16/neurintsurg-2017-013308.abstract
AB Objectives To evaluate the risk factors for rupture of intracranial aneurysms (IAs) using high resolution MRI (HRMRI).Methods 91 consecutive patients with 106 IAs were reviewed from February 2016 to April 2017. Patients and IAs were divided into ruptured and unruptured groups. In addition to the clinical characteristics of the patients, the features of IAs (eg, shape) were evaluated by CT angiography, whereas wall thickness, enhanced patterns, and enhancement ratio (ER) were evaluated by MRI. Multiple logistic regression analysis was used to identify independent risk factors associated with the rupture of IAs. Receiver operating characteristic curve analysis was performed on the final model, and the optimal thresholds were obtained.Results ER (OR 6.638) and partial wall enhancement (PWE) (OR 6.710) were not markers of aneurysms more prone to rupture, but simply were more commonly found in the ruptured aneurysm cohort. The threshold value for ER was 61.5%.Conclusions ER (≥61.5%) and IAs with PWE are better predictors of rupture. Increased attentions should be paid to these factors during assessment of IA rupture.