Endpoints | Time to treatment | p Value | |
---|---|---|---|
≤8 h (N=173) | >8 h (N=74) | ||
Mean age (years) | 67 | 64 | 0.054 (NS) |
Gender (M/F) | 78/95 (45.1/54.9) | 38/36 (51.4/48.6) | 0.405 (NS) |
Mean time to treatment (h) | 4.8 | 16.4 | <0.0001 |
90-day mRS≤2 (%) | 74 (42.8) | 31 (41.9) | 1.0 (NS) |
90-day mRS≤3 (%) | 95 (54.9) | 41 (55.4) | 1.0 (NS) |
Mortality (%) | 43 (24.9) | 15 (20.3) | 0.513 (NS) |
Intravenous tPA (%) | 95 (55.2) | 20 (27.0) | <0.0001 |
Recanalization | |||
Complete (TICI 2B or 3) (%) | 124 (71.7) | 60 (81.1) | 0.151 (NS) |
None (%) | 49 (28.3) | 14 (18.9) | |
Mean NIHSS | 18.7 | 17.2 | 0.069 (NS) |
Location of occlusion | |||
Anterior circulation (MCA or ICA) | 158 (92.4) | 61 (83.6) | 0.062 (NS) |
Isolated MCA occlusion | 119 (69.6) | 49 (67.1) | 0.763 (NS) |
Intracranial hemorrhage | 34 (19.7) | 14 (18.9) | 1.0 (NS) |
Symptomatic hemorrhage | 15 (8.7) | 5 (6.8) | 0.80 (NS) |
ICA, internal carotid artery; MCA, middle cerebral artery; mRS, modified Rankin Score; NIHSS, National Institutes of Health Stroke Scale; TICI, thrombolysis in cerebral infarction; tPA, tissue plasminogen activator.