Univariate analysis of predictors of parenchymal hematoma after endovascular stroke therapy
| Variable | PH (n=96) (N (%)) | No ICH (n=759) (N (%)) | p Value |
|---|---|---|---|
| Demographics | |||
| Age (years) (mean±SD) | 69±14 | 66±16 | 0.09 |
| NIHSS (mean±SD) | 18±6 | 16±6 | 0.009 |
| Female | 50 (52) | 393 (52) | 0.85 |
| Diabetes mellitus | 21 (22) | 156 (21) | 0.44 |
| Hypertension | 73 (76) | 518 (68) | 0.09 |
| Atrial fibrillation | 48 (50) | 265 (35) | 0.003 |
| Time to treatment (min±SD) | 290±139 | 296±162 | 0.75 |
| TIMI 2–3 recanalization | 67 (70) | 520 (69) | 0.91 |
| Clot location | |||
| M1 MCA | 52 (54) | 369 (49) | 0.18 |
| Carotid terminus | 16 (17) | 142 (19) | 0.37 |
| Tandem occlusion | 13 (14) | 94 (12) | 0.74 |
| M2 MCA | 13 (13) | 129 (17) | 0.47 |
| Extracranial ICA | 2 (2) | 25 (3) | 0.76 |
| Therapy | |||
| IV tPA | 29 (30) | 234 (31) | 0.50 |
| Merci embolectomy | 61 (63) | 411 (54) | 0.05 |
| Penumbra thrombectomy | 14 (15) | 88 (12) | 0.25 |
| Angioplasty | 27 (28) | 189 (25) | 0.53 |
| Stent placement | 21 (22) | 145 (19) | 0.31 |
| IA tPA | 39 (41) | 408 (54) | 0.009 |
| Pharmacologic therapy only | 15 (16) | 191 (25) | 0.02 |
| Mechanical therapy only | 34 (35) | 184 (24) | 0.014 |
| Multimodal therapy only | 47 (49) | 385 (51) | 0.41 |
ICA, internal carotid artery; ICH, intracranial hemorrhage; MCA, middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale; PH, parenchymal hematoma; TIMI, Thrombolysis in Myocardial Infarction; tPA, tissue plasminogen activator.