Comparison of the results of clinical trials employing different devices for mechanical thrombectomy for acute ischemic stroke
| Trial | Merci 2002–200712 | Penumbra 2007–200934 | SWIFT5 2012 | TREVO 20126 |
|---|---|---|---|---|
| Patients | 1511 1642 | 1253 1574 | 895 | 886 |
| Mean NIHSS | 20.11 192 | 17.63 16.64 | 17.45 | 18.36 |
| Symptom onset to treatment (h) | 4.31 4.32 | 4.33 4.14 | 4.85 | 4.66 |
| Treatment onset to recanalization time (min) | 1261 962 | 453 414 | 36*5 | 44*6 |
| Procedure complication (%) | 131 9.82 | 12.83 5.84 | 15.75 | 156 |
| Mortality at 90 days (%) | 43.51 342 | 333 204 | 175 | 336 |
| mRS ≤2 at 90 days (%) | 27.71 362 | 253 414 | 365 | 406 |
| Recanalization rate (%) | 481 682 | 823 874 | 615 | 86.46 |
*Recanalization time defined as the time from baseline guide catheter run to visualization of Thrombolysis In Myocardial Infarction (TIMI).
mRS, modified Rankin Scale; NIHSS, NIH Stroke Scale.