Effect of baseline characteristics and recanalization outcomes on risk of poor 90-day outcome (mRS 3–6)
| N (%) with risk factor | ||||||||
|---|---|---|---|---|---|---|---|---|
| Good (mRS 0–2) | Poor (mRS 3–6) | Crude OR | 95% CI | p Value | Adjusted OR | 95% CI | p Value | |
| Baseline characteristics | ||||||||
| Age ≥80 vs <80 years | 20/118 (17) | 33/116 (28) | 1.95 | (1.04 to 3.65) | 0.037 | 2.50 | (1.21 to 5.19) | 0.014 |
| Male vs female | 52/117 (44) | 62/116 (53) | 1.44 | (0.86 to 2.40) | 0.170 | – | – | – |
| Black vs white | 19/117 (16) | 20/116 (17) | 1.09 | (0.54 to 2.18) | 0.810 | – | – | – |
| Other race vs white | 7/117 (6) | 8/116 (7) | 1.18 | (0.41 to 3.40) | 0.757 | – | – | – |
| Smoking | 39/117 (33) | 28/114 (25) | 0.65 | (0.37 to 1.16) | 0.143 | – | – | – |
| Atrial fibrillation | 46/118 (39) | 52/116 (45) | 1.27 | (0.76 to 2.14) | 0.366 | – | – | – |
| Diabetes mellitus | 22/118 (19) | 39/116 (34) | 2.21 | (1.21 to 4.04) | 0.010 | 2.82 | (1.37 to 5.83) | 0.005 |
| Hypertension | 85/118 (72) | 89/116 (77) | 1.28 | (0.71 to 2.31) | 0.412 | – | – | – |
| Hyperlipidemia | 61/118 (52) | 63/116 (54) | 1.11 | (0.66 to 1.86) | 0.689 | – | – | – |
| Coronary artery disease | 34/118 (29) | 42/116 (36) | 1.40 | (0.81 to 2.43) | 0.228 | – | – | – |
| ICA/basilar site vs M1/M2 | 29/118 (25) | 46/116 (40) | 2.02 | (1.15 to 3.53) | 0.014 | 2.18 | (1.10 to 4.33) | 0.026 |
| NIHSS ≥18 vs ≤17 | 42/117 (36) | 73/111 (66) | 3.43 | (1.99 to 5.91) | <0.001 | 4.51 | (2.33 to 8.71) | <0.001 |
| Recanalization outcomes | ||||||||
| Final TICI 2b vs 3 | 46/118 (39) | 61/116 (53) | 1.74 | (1.03 to 2.92) | 0.037 | – | – | – |
| Rescue therapy, Solitaire failed | 12/118 (10) | 36/116 (31) | 3.97 | (1.94 to 8.12) | <0.001 | 4.94 | (2.14 to 11.43) | <0.001 |
| Distal embolization | 20/116 (17) | 16/116 (14) | 0.77 | (0.38 to 1.57) | 0.469 | – | – | – |
| Balloon-guided catheter not used | 54/113 (48) | 72/111 (65) | 2.02 | (1.18 to 3.45) | 0.010 | – | – | – |
| Solitaire+Penumbra | 14/113 (12) | 18/111 (16) | 1.37 | (0.64 to 2.91) | 0.414 | – | – | – |
| Intra-arterial t-PA not used | 89/118 (75) | 80/116 (69) | 0.72 | (0.41 to 1.29) | 0.271 | – | – | – |
| Intravenous t-PA not used | 57/118 (48) | 76/115 (66) | 2.09 | (1.23 to 3.54) | 0.006 | 2.81 | (1.47 to 5.36) | 0.002 |
| Passes ≥3 vs 1–2 | 13/117 (11) | 22/116 (19) | 1.87 | (0.89 to 3.93) | 0.097 | 2.62 | (1.03 to 6.69) | 0.043 |
| Time to recanalization ≥30 min vs <30 min | 69/105 (66) | 86/104 (83) | 2.49 | (1.28 to 4.59) | 0.006 | – | – | – |
p Value: Wald statistic. ORs estimate the risk of a poor 90-day outcome for patients with versus without the factor shown at left except where other categories are indicated. Crude ORs were estimated from univariate logistic regression; adjusted ORs from a multivariable model with the covariates shown (226 cases).
ICA, internal carotid artery; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; TICI, Thrombolysis in Cerebral Infarction; t-PA, tissue plasminogen activator.