Table 1

Patient characteristics

VariableNo of patientsTotal‘Early recan’‘Late recan’p Value
≤35 min>35 min
Preprocedure
 Age (years)19766.3 (14)64.2 (14.1)69.9 (13.3)0.005
 Female, n (%)19790 (45.7)55 (45.1)35 (46.7)0.828
 White, n (%)197112 (56.9)67 (54.9)45 (60)0.484
 Baseline NIHSS19715.2 (7)14.7 (6.9)15.9 (7.2)0.207
 Time from onset to groin (h)1627.9 (6.1)8.35 (6.54)7.03 (5.05)0.19
 IV tPA, n (%)19770 (35.5)46 (37.7)24 (32)0.417
 Proximal occlusion197141 (71.6)85 (69.7)56 (74.7)0.450
Comorbidities, n (%)
 AF18842 (22.3)29 (24.8)13 (18.3)0.301
 Diabetes18839 (20.7)25 (21.4)14 (19.7)0.787
 Hypertension188124 (66.0)71 (60.7)53 (74.6)0.051
Procedure
 Time to recanalization (min)19737.7 (35.9)17.8 (8.8)70 (39.8)<0.001
 Final TICI flow, n (%)197<0.001
  01 (0.5)1 (0.8)0 (0.0)
  13 (1.5)0 (0.00)3 (4)
  2a3 (1.5)0 (0.00)3 (4)
  2b57 (28.9)26 (21.3)31 (41.3)
  2c16 (8.1)12 (9.8)4 (5.3)
  3117 (59.4)83 (68)34 (45.3)
 Final TICI flow, n (%)1970.013
  0–2a7 (3.6)1 (0.8)6 (8.0)
  2b–3190 (96.4)121 (99.2)69 (92.0)
 Complications, n (%)1972 (1.0)1 (0.8)1 (1.3)0.999
 Hemorrhage, all types (n (%))19762 (31.5)29 (23.8)33 (44.0)0.003
  Hemorrhage, PH219713 (6.6)3 (2.5)10 (13.3)0.006
  Hemorrhage, others19749 (24.9)26 (21.3)23 (30.7)0.140
 Device, n (%)
  Stent retrievers*19746 (23.4)16 (13.1)30 (40.0)<0.001
  Carotid stenting19710 (5.1)2 (1.6)8 (11.3)0.007
  Other197143 (72.6)105 (86.1)38 (50.7)<0.001
 Number of passes197<0.001
  175 (38.1)60 (49.2)15 (20.0)
  280 (40.6)46 (37.7)34 (45.3)
  335 (17.8)16 (13.1)19 (25.3)
  47 (3.6)0 (0.0)7 (9.3)
 Number of ADAPT passes1970.115
  1100 (50.8)68 (55.7)32 (42.7)
  281 (41.1)47 (38.5)34 (45.3)
  316 (8.1)7 (5.7)9 (12.0)
Outcome (90 day)
 mRS dichotomized, n (%)180<0.001
  mRS 0–299 (55)73 (65.2)26 (38.2)
  mRS >281 (45)39 (34.8)42 (61.8)
 Death, n (%)19729 (14.7)13 (10.7)16 (21.3)0.040
 NIHSS (90 days)982.3 (3.4)1.7 (2.9)3.3 (4.1)0.034
 Length of stay (days)1888.7 (17.1)8.2 (12.9)9.5 (22.5)0.612
  • Values are n (%) or mean (SD).

  • χ2 test (Fisher's exact test for small cell sizes) or Student's t test for the entire patient cohort.

  • *Stent retrievers include Solitaire and Trevo.

  • Additionally, we dichotomized the cohort into patients in whom recanalization times were achieved in ≤35 min ‘early recan’) and those in whom recanalization times extended beyond 35 min (‘late recan’).

  • ADAPT, a direct aspiration first pass technique; AF, atrial fibrillation; IV tPA, IV tissue plasminogen activator; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; PH2, parenchymal hematoma type 2; TICI, Thrombolysis in Cerebral Infarction.