Table 2

Mixed model pairwise comparisons between levels of each variable

Effect	Comparison	Estimate	90% CI upper	90% CI lower	P value
Location	Middle vs proximal	−0.183	−0.627	−0.262	0.493
	Middle vs distal	0.417	−0.027	0.862	0.122
	Proximal vs distal	0.6	0.156	1.04	0.028
Time	Week 2 vs control	−0.653	−1.81	0.503	0.340
	Week 4 vs control	−2.18	−3.39	−0.974	0.006
	Week 8 vs control	−1.65	−2.81	−0.497	0.023
	Week 12 vs control	−0.844	−1.96	0.275	0.207
	Week 2 vs week 4	1.53	0.468	2.59	0.022
	Week 2 vs week 8	1	−0.001	2	0.100
	Week 4 vs week 8	−0.53	−1.59	−0.532	0.398
	Week 2 vs week 12	0.191	−0.768	1.15	0.734
	Week 4 vs week 12	−1.34	−2.36	0.317	0.036
	Week 8 vs week 12	−0.809	−1.77	0.15	0.161