Hemodynamic parameters | No of studies | No of IAs | Mean difference | 95% CI of difference | SD | P value | |
Overlapping | IR reduction (%) | 4 | 7 | −14.4 | −19.6 to −9.3 | 5.6 | 0.0005* |
AAV reduction (%) | 6 | 9 | −16.8 | −23.5 to −10.1 | 8.7 | 0.0004* | |
WSS reduction (%) | 4 | 6 | −27.3 | −31.4 to −23.3 | 3.9 | <0.0001* | |
TUT change (%) | 2 | 4 | 47.0 | 11.3 to 82.7 | 22.4 | 0.0247† | |
Compaction | IR reduction (%) | 4 | 8 | −16.0 | −25.4 to −6.7 | 11.3 | 0.0051† |
AAV reduction (%) | 3 | 6 | −23.3 | −38.4 to −8.3 | 14.4 | 0.0105† | |
TUT change (%) | 2 | 4 | 58.3 | −12.5 to 129.0 | 44.5 | 0.0791 |
*Statistical significance confirmed (p<0.005).
†Suggestive of statistical significance (p<0.05).
AAV, intra-aneurysmal average velocity; IA, intracranial aneurysm; IR, inflow rate; TUT, turnover time; WSS, wall shear stress.