CT perfusion imaging in acute stroke

Angelos A Konstas; Max Wintermark; Michael H Lev

doi:10.1016/j.nic.2011.01.008

CT perfusion imaging in acute stroke

Neuroimaging Clin N Am. 2011 May;21(2):215-38, ix. doi: 10.1016/j.nic.2011.01.008.

Authors

Angelos A Konstas¹, Max Wintermark, Michael H Lev

Affiliation

¹ Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA. akonstas@partners.org

PMID: 21640296
DOI: 10.1016/j.nic.2011.01.008

Abstract

Computed tomographic perfusion (CTP) imaging is an advanced modality that provides important information about capillary-level hemodynamics of the brain parenchyma. CTP can aid in diagnosis, management, and prognosis of acute stroke patients by clarifying acute cerebral physiology and hemodynamic status, including distinguishing severely hypoperfused but potentially salvageable tissue from both tissue likely to be irreversibly infarcted ("core") and hypoperfused but metabolically stable tissue ("benign oligemia"). A qualitative estimate of the presence and degree of ischemia is typically required for guiding clinical management. Radiation dose issues with CTP imaging, a topic of much current concern, are also addressed in this review.

Publication types

Review

MeSH terms

Cerebral Angiography / methods*
Cerebral Hemorrhage / complications*
Cerebral Hemorrhage / diagnosis*
Humans
Perfusion Imaging / methods*
Radiographic Image Enhancement / methods*
Stroke / complications*
Stroke / diagnosis*
Tomography, X-Ray Computed / methods*