Abstract Purpose Silent corticotroph adenomas (SCAs) are clinically silent and non-
secreting, but exhibit positive adrenocorticotropic hormone (ACTH) immunostaining. We …

This study examined the time course of the blood–brain barrier (BBB) opening and
correlated this with brain edema formation after a lateral controlled cortical impact (CCI) …

Excess activation of NMDA receptors is felt to participate in secondary neuronal damage
after traumatic brain injury (TBI). Increased extracellular glutamate is active in this process …

Transient focal cerebral ischemia leads to extensive neuronal damage in cerebral cortex
and striatum. Normal functioning of glutamate transporters clears the synaptically released …

In mammalian CNS, the peripheral-type benzodiazepine receptor (PTBR) is localized on the
outer mitochondrial membrane within the astrocytes and microglia. PTBR transports …

This study investigated whether memantine, a non-competitive NMDA receptor antagonist is
neuroprotective after traumatic brain injury (TBI) induced in adult rats with a controlled …

Object. Cytidine 5′-diphosphocholine (CDPC), or citicoline, is a naturally occurring
endogenous compound that has been reported to provide neuroprotective effects after …

Traumatic injury to rat brain induced by controlled cortical impact (CCI) results in chronic
neuronal death in the hippocampus. In the normal brain, glutamate transporters actively …

Object The optimal timing of cranioplasty after decompressive craniectomy for stroke is not
known. Case series suggest that early cranioplasty is associated with higher rates of …

Background Lumboperitoneal shunt (LPS), ventriculoperitoneal shunt (VPS) and optic nerve
sheath fenestration (ONSF) are accepted surgical therapies for medically refractory …