User profiles for "author:C Dowd"

Cynthia Dowd

Associate Professor, George Washington University
Verified email at email.gwu.edu
Cited by 3572

Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily

D Sheehan, G Meade, VM Foley… - Biochemical journal, 2001 - portlandpress.com
The glutathione transferases (GSTs; also known as glutathione S-transferases) are major
phase II detoxification enzymes found mainly in the cytosol. In addition to their role in …

Intravascular stent and endovascular coil placement for a ruptured fusiform aneurysm of the basilar artery: case report and review of the literature

RT Higashida, W Smith, D Gress, R Urwin… - Journal of …, 1997 - thejns.org
✓ The authors demonstrate the technical feasibility of using intravascular stents in
conjunction with electrolytically detachable coils (Guglielmi detachable coils [GDCs]) for …

The many faces of PHACE syndrome

DW Metry, CF Dowd, AJ Barkovich, IJ Frieden - The Journal of pediatrics, 2001 - Elsevier
Objectives: PHACE is an acronym coined to describe a neurocutaneous syndrome
encompassing the following features: posterior fossa brain malformations, large facial …

PA-824 Kills Nonreplicating Mycobacterium tuberculosis by Intracellular NO Release

R Singh, U Manjunatha, HIM Boshoff, YH Ha… - Science, 2008 - science.org
Bicyclic nitroimidazoles, including PA-824, are exciting candidates for the treatment of
tuberculosis. These prodrugs require intracellular activation for their biological function. We …

Predictors of rehemorrhage after treatment of ruptured intracranial aneurysms: the Cerebral Aneurysm Rerupture After Treatment (CARAT) study

SC Johnston, CF Dowd, RT Higashida, MT Lawton… - Stroke, 2008 - Am Heart Assoc
Background and Purpose—The primary purpose of intracranial aneurysm treatment is to
prevent rupture. Risk factors for rupture after aneurysm treatment have not been clearly …

Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis

UH Manjunatha, H Boshoff, CS Dowd… - Proceedings of the …, 2006 - National Acad Sciences
PA-824 is a promising new compound for the treatment of tuberculosis that is currently
undergoing human trials. Like its progenitors metronidazole and CGI-17341, PA-824 is a …

Endovascular and surgical treatment of unruptured cerebral aneurysms: comparison of risks

S Claiborne Johnston, CB Wilson… - Annals of …, 2000 - Wiley Online Library
Unruptured cerebral aneurysms are commonly treated by surgical clipping, but
endovascular coil embolization is increasingly employed as an alternative. In a blinded …

Dural carotid cavernous fistula: definitive endovascular management and long-term follow-up

PM Meyers, VV Halbach, CF Dowd, TE Lempert… - American journal of …, 2002 - Elsevier
PURPOSE: To describe the endovascular treatment and clinical outcome in patients with
indirect carotid cavernous fistulas (CCFs) over a 15-year period. To our knowledge, this is …

The Cystic Fibrosis Foundation Patient Registry. Design and methods of a national observational disease registry

…, CH Goss, A Sewall, J Ostrenga, C Dowd… - Annals of the …, 2016 - atsjournals.org
Rationale: The Cystic Fibrosis Foundation Patient Registry (CFFPR) is an ongoing patient
registry study that collects longitudinal demographic, clinical, and treatment information …

Development of acquired arteriovenous fistulas in rats due to venous hypertension

T Terada, RT Higashida, VV Halbach, CF Dowd… - Journal of …, 1994 - thejns.org
✓ Dural sinus thrombosis has been hypothesized as a possible cause of dural arteriovenous
fistulas (AVF's). The pathogenesis and evolution from thrombosis to actual development of …