Management of tandem occlusions in acute ischemic stroke–intracranial versus extracranial first and extracranial stenting versus angioplasty alone: a systematic …

…, MH Murad, T Krings, VM Pereira, C O'Kelly… - Journal of …, 2018 - jnis.bmj.com
Background Optimal technical approaches of large-vessel anterior circulation acute
ischemic strokes with concomitant extracranial internal carotid artery tandem occlusions is …

Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial

…, R Owen, R Ashforth, T Yeo, T Kotylak, C O'Kelly - The Lancet, 2020 - thelancet.com
Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …

The natural history and predictive features of hemorrhage from brain arteriovenous malformations

L da Costa, MC Wallace, KG Ter Brugge, C O'Kelly… - Stroke, 2009 - Am Heart Assoc
Background and Purpose— Patients harboring brain arteriovenous malformations (bAVMs)
are at a lifelong risk for hemorrhagic strokes, but the natural history is poorly understood. We …

Shunt-dependent hydrocephalus after aneurysmal subarachnoid hemorrhage: incidence, predictors, and revision rates

CJ O'Kelly, AV Kulkarni, PC Austin, D Urbach… - Journal of …, 2009 - thejns.org
Object Chronic shunt-dependent hydrocephalus is a recognized complication of aneurysmal
subarachnoid hemorrhage. While its incidence and risk factors have been well described, …

Canadian stroke best practice recommendations: Management of Spontaneous Intracerebral Hemorrhage, 7th Edition Update 2020

…, T Huynh, M Kelly, CJ O'Kelly… - … journal of stroke, 2021 - journals.sagepub.com
Spontaneous intracerebral hemorrhage is a particularly devastating type of stroke with greater
morbidity and mortality compared with ischemic stroke and can account for half or more of …

Surgical clipping or endovascular coiling for unruptured intracranial aneurysms: a pragmatic randomised trial

…, F Scholtes, D Martin, MM Chow, CJ O'Kelly… - Journal of Neurology …, 2017 - jnnp.bmj.com
Background Unruptured intracranial aneurysms (UIAs) are increasingly diagnosed and are
commonly treated using endovascular treatment or microsurgical clipping. The safety and …

Adherence to brain trauma foundation guidelines for management of traumatic brain injury patients and its effect on outcomes: systematic review

…, S Campbell, A Senthilselvan, C O'kelly… - Journal of …, 2018 - liebertpub.com
Traumatic brain injury (TBI) management based on Brain Trauma Foundation (BTF) guidelines
is widely accepted and thought to improve outcome. The objectives of this study are to …

Predicting recurrence after chronic subdural haematoma drainage

A Jack, C O'Kelly, C McDougall… - Canadian Journal of …, 2015 - cambridge.org
Background: Recurrence of chronic subdural haematomas (CSDHs) after surgical drainage
is a significant problem with rates up to 20%. This study focuses on determining factors …

The production of scoliosis after pinealectomy in young chickens, rats, and hamsters

C O'Kelly, X Wang, J Raso, M Moreau, J Mahood… - Spine, 1999 - journals.lww.com
Study Design. This study involved weekly radiographic examination of pinealectomized rats,
hamsters, and chickens to observe the development of scoliosis. Objectives. To determine …

The second-generation eCLIPs endovascular clip system: initial experience

AH Chiu, J De Vries, CJ O'Kelly, H Riina… - Journal of …, 2017 - thejns.org
OBJECTIVE Treatment of wide-necked intracranial aneurysms is associated with higher
recanalization and complication rates; however, the most commonly used methods are not …