The purpose of this review is to describe recent clinical and epidemiological studies
examining the adverse effects of urban air pollution on the central nervous system (CNS). Air …

Murine chronic cerebral hypoperfusion (CCH) results in white matter (WM) injury and
behavioral deficits. Pericytes influence blood–brain barrier (BBB) integrity and cerebral …

Epidemiological studies have established an association between air pollution particulate
matter exposure (PM2. 5) and neurocognitive decline. Experimental data suggest that …

Intracerebral hemorrhage and, more specifically, intraparenchymal hemorrhage, are
devastating disease processes with poor clinical outcomes. Primary injury to the brain …

Objectives: Chronic cerebral hypoperfusion (CCH) can result in vascular dementia and
small vessel white matter ischemic injury. These findings have previously been …

Background and Purpose Estradiol is a sex steroid hormone known to protect the brain
against damage related to transient and global cerebral ischemia. In the present study, we …

This study examines the effects of nano-size particulate matter (nPM) exposure in the setting
of murine reperfused stroke. Particulate matter is a potent source of inflammation and …

National and regional systems of stroke care are designed to provide patients with
widespread access to hospitals with thrombolytic capabilities. However, such triaging …

Background: Clinical and epidemiologic studies suggest a relationship between long-term
nano-particulate matter (nPM) exposure and white matter injury1. Accumulating laboratory …