Scientific rationale for the inclusion and exclusion criteria for intravenous alteplase in acute ischemic stroke: a statement for healthcare professionals from the …
BM Demaerschalk, DO Kleindorfer, OM Adeoye… - Stroke, 2016 - Am Heart Assoc
Purpose—To critically review and evaluate the science behind individual eligibility criteria
(indication/inclusion and contraindications/exclusion criteria) for intravenous recombinant …
(indication/inclusion and contraindications/exclusion criteria) for intravenous recombinant …
Short‐chain fatty acids: ready for prime time?
The concept of colonic health has become a major target for the development of functional
foods such as probiotics, prebiotics, and synbiotics. These bioactive agents have a profound …
foods such as probiotics, prebiotics, and synbiotics. These bioactive agents have a profound …
Oxidative stress as a critical factor in nonalcoholic fatty liver disease pathogenesis
Significance: Nonalcoholic fatty liver disease (NAFLD), characterized by liver triacylglycerol
build-up, has been growing in the global world in concert with the raised prevalence of …
build-up, has been growing in the global world in concert with the raised prevalence of …
[HTML][HTML] Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct
RG Nogueira, AP Jadhav, DC Haussen… - … England Journal of …, 2018 - Mass Medical Soc
Background The effect of endovascular thrombectomy that is performed more than 6 hours
after the onset of ischemic stroke is uncertain. Patients with a clinical deficit that is …
after the onset of ischemic stroke is uncertain. Patients with a clinical deficit that is …
Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials
Background In 2015, five randomised trials showed efficacy of endovascular thrombectomy
over standard medical care in patients with acute ischaemic stroke caused by occlusion of …
over standard medical care in patients with acute ischaemic stroke caused by occlusion of …
[HTML][HTML] Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke
Background Among patients with acute ischemic stroke due to occlusions in the proximal
anterior intracranial circulation, less than 40% regain functional independence when treated …
anterior intracranial circulation, less than 40% regain functional independence when treated …
Independent association between acute renal failure and mortality following cardiac surgery
GM Chertow, EM Levy, KE Hammermeister… - The American journal of …, 1998 - Elsevier
Purpose: To determine whether there is an independent association of acute renal failure
requiring dialysis with operative mortality after cardiac surgery. Patients and Methods: The …
requiring dialysis with operative mortality after cardiac surgery. Patients and Methods: The …
[HTML][HTML] Faulty autolysosome acidification in Alzheimer's disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques
…, MJ Berg, C Huo, J Peddy, M Pawlik, E Levy… - Nature …, 2022 - nature.com
Autophagy is markedly impaired in Alzheimer's disease (AD). Here we reveal unique
autophagy dysregulation within neurons in five AD mouse models in vivo and identify its …
autophagy dysregulation within neurons in five AD mouse models in vivo and identify its …
[HTML][HTML] Stenting versus aggressive medical therapy for intracranial arterial stenosis
MI Chimowitz, MJ Lynn, CP Derdeyn… - … England Journal of …, 2011 - Mass Medical Soc
Background Atherosclerotic intracranial arterial stenosis is an important cause of stroke that
is increasingly being treated with percutaneous transluminal angioplasty and stenting …
is increasingly being treated with percutaneous transluminal angioplasty and stenting …
The effect of acute renal failure on mortality: a cohort analysis
EM Levy, CM Viscoli, RI Horwitz - Jama, 1996 - jamanetwork.com
Objective.—To determine if the high mortality in acute renal failure is explained by
underlying illnesses (comorbidity). Design.—Cohort analytic study. Setting.—An 826-bed …
underlying illnesses (comorbidity). Design.—Cohort analytic study. Setting.—An 826-bed …