Spreading depolarizations (SD) are waves of abrupt, near-complete breakdown of neuronal
transmembrane ion gradients, are the largest possible pathophysiologic disruption of viable …

BACKGROUND: Compression of the third nerve resulting in oculomotor nerve palsy (ONP)
is a common initial symptom and in some cases the only neurological deficit in patients with …

Object Quality and safety are basic concerns in any medical practice. Especially in daily
surgical practice, with increasing turnover and shortened procedure times, attention to these …

Decompressive craniectomy (DC) due to intractably elevated intracranial pressure
mandates later cranioplasty (CP). However, the optimal timing of CP remains controversial …

Glycine and GABA, the dominant inhibitory neurotransmitters in the CNS, assume a
depolarizing role in early development, leading to increased cytoplasmic Ca2+ levels and …

Object The objective of this study was to analyze whether age influences the outcome of
patients with glioblastoma and whether elderly patients with glioblastoma can tolerate the …

OBJECTIVE: To analyze the incidence and impact of an intracerebral hematoma (ICH) on
treatment and outcome in patients with aneurysmal subarachnoid hemorrhage. METHODS …

Focal brain damage after aneurysmal subarachnoid haemorrhage predominantly results
from intracerebral haemorrhage, and early and delayed cerebral ischaemia. The …

Aseptic bone flap resorption (BFR) is a known long-term complication after cranioplasty
(CP). We analyzed our institutional data in order to identify risk factors for BFR. From October …

Background Chronic subdural haematoma (cSDH) is a common disease in neurosurgical
practise, especially in elderly patients. This is of growing importance as the number of …