Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models
Platelets are crucial for normal hemostasis; however, their hyperactivation also contributes
to many potentially lethal pathologies including myocardial infarction, stroke, and cancer …
to many potentially lethal pathologies including myocardial infarction, stroke, and cancer …
Quantitative assessment of device–clot interaction for stent retriever thrombectomy
K van der Marel, JY Chueh, OW Brooks… - Journal of …, 2016 - jnis.bmj.com
Purpose Rapid revascularization in emergent large vessel occlusion with endovascular
embolectomy has proven clinical benefit. We sought to measure device–clot interaction as a …
embolectomy has proven clinical benefit. We sought to measure device–clot interaction as a …
Acute thrombus formation on phosphorilcholine surface modified flow diverters
M Marosfoi, F Clarencon, ET Langan… - Journal of …, 2018 - jnis.bmj.com
Purpose Thromboembolic complications remain a limitation of flow diverting stents. We
hypothesize that phosphorilcholine surface modified flow diverters (Pipeline Flex with Shield …
hypothesize that phosphorilcholine surface modified flow diverters (Pipeline Flex with Shield …
[HTML][HTML] A neurovascular high-frequency optical coherence tomography system enables in situ cerebrovascular volumetric microscopy
Intravascular imaging has emerged as a valuable tool for the treatment of coronary and
peripheral artery disease; however, no solution is available for safe and reliable use in the …
peripheral artery disease; however, no solution is available for safe and reliable use in the …
Communicating malapposition of flow diverters assessed with optical coherence tomography correlates with delayed aneurysm occlusion
RM King, OW Brooks, ET Langan, J Caroff… - Journal of …, 2018 - jnis.bmj.com
Background Optical coherence tomography (OCT) is a high resolution intravascular imaging
method that allows visualization of flow diverter struts and the vessel wall. In this study …
method that allows visualization of flow diverter struts and the vessel wall. In this study …
Shear-activated nanoparticle aggregates combined with temporary endovascular bypass to treat large vessel occlusion
Background and Purpose—The goal of this study is to combine temporary endovascular
bypass (TEB) with a novel shear-activated nanotherapeutic (SA-NT) that releases …
bypass (TEB) with a novel shear-activated nanotherapeutic (SA-NT) that releases …
Phosphorylcholine surface modified flow diverter associated with reduced intimal hyperplasia
Background Optical coherence tomography (OCT) is a high-resolution, intra-vascular
diagnostic technique widely used for the characterization of vascular pathologies and …
diagnostic technique widely used for the characterization of vascular pathologies and …
In situ tissue engineering: endothelial growth patterns as a function of flow diverter design
M Marosfoi, ET Langan, L Strittmatter… - Journal of …, 2017 - jnis.bmj.com
Background Vascular remodeling in response to implantation of a tissue engineering
scaffold such as a flow diverter (FD) leads to the cure of intracranial aneurysms. We …
scaffold such as a flow diverter (FD) leads to the cure of intracranial aneurysms. We …
Microcatheter navigation through the clot: does size matter?
J Caroff, RM King, R Arslanian, M Marosfoi… - Journal of …, 2019 - jnis.bmj.com
Background Despite high recanalization rates achieved with endovascular treatment of
acute ischemic strokes, around 50% of eligible patients will not achieve a good outcome …
acute ischemic strokes, around 50% of eligible patients will not achieve a good outcome …
Acute thrombus burden on coated flow diverters assessed by high frequency optical coherence tomography
RM King, ET Langan, GJ Ughi, CM Raskett… - Cardiovascular and …, 2020 - Springer
Purpose The implantation of flow diverters requires administration of dual anti-platelet
therapy, posing the potential for complications. The p48MW HPC (phenox, Bochüm …
therapy, posing the potential for complications. The p48MW HPC (phenox, Bochüm …