Background Trials examining the benefit of thrombectomy in anterior circulation proximal
large vessel occlusion stroke have enrolled patients considered to have salvageable brain …

Hypertension Canada's 2020 guidelines for the prevention, diagnosis, risk assessment, and
treatment of hypertension in adults and children provide comprehensive, evidence-based …

Abstract The Canadian Hypertension Education Program reviews the hypertension literature
annually and provides detailed recommendations regarding hypertension diagnosis …

Background Among patients with a proximal vessel occlusion in the anterior circulation, 60
to 80% of patients die within 90 days after stroke onset or do not regain functional …

Background In 2015, five randomised trials showed efficacy of endovascular thrombectomy
over standard medical care in patients with acute ischaemic stroke caused by occlusion of …

Background Carotid-artery stenting and carotid endarterectomy are both options for treating
carotid-artery stenosis, an important cause of stroke. Methods We randomly assigned …

Background Trials of the efficacy and safety of endovascular thrombectomy in patients with
large ischemic strokes have been carried out in limited populations. Methods We performed …

Background Endovascular therapy is increasingly used after the administration of
intravenous tissue plasminogen activator (t-PA) for patients with moderate-to-severe acute …

Importance Endovascular thrombectomy with second-generation devices is beneficial for
patients with ischemic stroke due to intracranial large-vessel occlusions. Delineation of the …

Background Although the use of magnetic resonance imaging (MRI) for the diagnosis of
acute stroke is increasing, this method has not proved more effective than computed …