[HTML][HTML] Randomized assessment of rapid endovascular treatment of ischemic stroke

M Goyal, AM Demchuk, BK Menon… - … England Journal of …, 2015 - Mass Medical Soc
Background Among patients with a proximal vessel occlusion in the anterior circulation, 60
to 80% of patients die within 90 days after stroke onset or do not regain functional …

Management of tandem occlusions in acute ischemic stroke–intracranial versus extracranial first and extracranial stenting versus angioplasty alone: a systematic …

MP Wilson, MH Murad, T Krings, VM Pereira… - Journal of …, 2018 - jnis.bmj.com
Background Optimal technical approaches of large-vessel anterior circulation acute
ischemic strokes with concomitant extracranial internal carotid artery tandem occlusions is …

Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials

M Goyal, BK Menon, WH Van Zwam, DWJ Dippel… - The Lancet, 2016 - thelancet.com
Background In 2015, five randomised trials showed efficacy of endovascular thrombectomy
over standard medical care in patients with acute ischaemic stroke caused by occlusion of …

Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial

MD Hill, M Goyal, BK Menon, RG Nogueira… - The Lancet, 2020 - thelancet.com
Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia …

Canadian association of radiologists guidance on contrast-associated acute kidney injury

DB Macdonald, CD Hurrell, AF Costa… - … Journal of Kidney …, 2022 - journals.sagepub.com
Purpose: Iodinated contrast media is one of the most frequently administered
pharmaceuticals. In Canada, over 5.4 million computed tomography (CT) examinations were …

[HTML][HTML] Safety and efficacy of solitaire stent thrombectomy

BCV Campbell, MD Hill, M Rubiera, BK Menon… - Stroke, 2016 - journals.lww.com
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Analysis of workflow and time to treatment on thrombectomy outcome in the endovascular treatment for small core and proximal occlusion ischemic stroke (ESCAPE) …

BK Menon, TT Sajobi, Y Zhang, JL Rempel, A Shuaib… - Circulation, 2016 - Am Heart Assoc
Background—The Endovascular Treatment for Small Core and Proximal Occlusion Ischemic
Stroke (ESCAPE) trial used innovative imaging and aggressive target time metrics to …

Connexin26 in adult rodent central nervous system: demonstration at astrocytic gap junctions and colocalization with connexin30 and connexin43

JI Nagy, X Li, J Rempel, G Stelmack… - Journal of …, 2001 - Wiley Online Library
The connexin family of proteins (Cx) that form intercellular gap junctions in vertebrates is
well represented in the mammalian central nervous system. Among these, Cx30 and Cx43 …

Endovascular treatment for Small Core and Anterior circulation Proximal occlusion with Emphasis on minimizing CT to recanalization times (ESCAPE) trial …

AM Demchuk, M Goyal, BK Menon… - … Journal of Stroke, 2015 - journals.sagepub.com
ESCAPE is a prospective, multicenter, randomized clinical trial that will enroll subjects with
the following main inclusion criteria: less than 12 h from symptom onset, age> 18, baseline …

Acute ischemic stroke with tandem lesions: technical endovascular management and clinical outcomes from the ESCAPE trial

Z Assis, BK Menon, M Goyal, AM Demchuk… - Journal of …, 2018 - jnis.bmj.com
Background Tandem occlusions of the extracranial carotid and intracranial carotid or middle
cerebral artery have a particularly poor prognosis without treatment. Several management …