Impact of thrombophilia on risk of arterial ischemic stroke or cerebral sinovenous thrombosis in neonates and children: a systematic review and meta-analysis of …
G Kenet, LK Lütkhoff, M Albisetti, T Bernard… - Circulation, 2010 - Am Heart Assoc
Background—The aim of this study was to estimate the impact of thrombophilia on risk of first
childhood stroke through a meta-analysis of published observational studies. Methods and …
childhood stroke through a meta-analysis of published observational studies. Methods and …
Stroke in newborn infants
KB Nelson, JK Lynch - The Lancet Neurology, 2004 - thelancet.com
The few days before and after birth are a time of special risk for stroke in both mother and
infant, probably related to activation of coagulation mechanisms in this critical period …
infant, probably related to activation of coagulation mechanisms in this critical period …
Neuronal nicotinic acetylcholine receptors as targets for drug discovery
MW Holladay, MJ Dart, JK Lynch - Journal of medicinal chemistry, 1997 - ACS Publications
Until recently, research on (S)-(-)-nicotine (1, hereafter simply nicotine) and nicotinic
acetylcholine receptors (nAChRs) emphasized two principal aspects. The first was the …
acetylcholine receptors (nAChRs) emphasized two principal aspects. The first was the …
Comparison of MRI and CT for detection of acute intracerebral hemorrhage
CS Kidwell, JA Chalela, JL Saver, S Starkman, MD Hill… - Jama, 2004 - jamanetwork.com
ContextNoncontrast computed tomography (CT) is the standard brain imaging study for the
initial evaluation of patients with acute stroke symptoms. Multimodal magnetic resonance …
initial evaluation of patients with acute stroke symptoms. Multimodal magnetic resonance …
Effects of conjugated equine estrogen on stroke in the Women's Health Initiative
SL Hendrix, S Wassertheil-Smoller, KC Johnson… - Circulation, 2006 - Am Heart Assoc
Background—The Women's Health Initiative (WHI) Estrogen Alone trial assessed the
balance of benefits and risks of hormone use in healthy postmenopausal women. The trial …
balance of benefits and risks of hormone use in healthy postmenopausal women. The trial …
Symptomatic neonatal arterial ischemic stroke: the International Pediatric Stroke Study
BACKGROUND: Neonatal arterial ischemic stroke (AIS) has emerged as a leading cause of
perinatal brain injury, cerebral palsy, and lifelong disability. The pathogenesis is poorly …
perinatal brain injury, cerebral palsy, and lifelong disability. The pathogenesis is poorly …
Diagnostic accuracy of magnetic resonance angiography for internal carotid artery disease: a systematic review and meta-analysis
SM Debrey, H Yu, JK Lynch, KO Lövblad, VL Wright… - Stroke, 2008 - Am Heart Assoc
Background and Purpose—Accurate diagnosis of the degree of internal carotid artery (ICA)
stenosis is needed for decisions regarding optimal stroke prevention. Noninvasive magnetic …
stenosis is needed for decisions regarding optimal stroke prevention. Noninvasive magnetic …
Predictors of acute stroke mimics in 8187 patients referred to a stroke service
Background Some patients seen by a stroke team do not have cerebrovascular disease but
a condition that mimics stroke. The purpose of this study was to determine the rate and …
a condition that mimics stroke. The purpose of this study was to determine the rate and …
Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor
G Zhao, AJ Souers, M Voorbach, HD Falls… - Journal of medicinal …, 2008 - ACS Publications
A highly potent and selective DGAT-1 inhibitor was identified and used in rodent models of
obesity and postprandial chylomicron excursion to validate DGAT-1 inhibition as a novel …
obesity and postprandial chylomicron excursion to validate DGAT-1 inhibition as a novel …
Perinatal arterial stroke: understanding mechanisms and outcomes
YW Wu, JK Lynch, KB Nelson - Seminars in neurology, 2005 - thieme-connect.com
Arterial ischemic infarction occurring around the time of birth is an increasingly recognized
cause of neurological disability in children. The rate of arterial infarction in neonates is as …
cause of neurological disability in children. The rate of arterial infarction in neonates is as …