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Background and Purpose: The Merci and Multi-Merci trials evaluated the safety and efficacy of endovascular thrombectomy with the Merci Retriever in the treatment of proximal intracranial arterial occlusions performed within 8 h of stroke symptom onset. We sought to determine whether time to reperfusion influences clinical outcomes in the context of anterior circulation thrombectomy. In addition, we investigated which baseline factors predict good clinical outcomes and mortality in successfully revascularized anterior circulation occlusion patients.
Methods: The subjects of this study included all patients in the Merci/Multi-Merci studies who presented with occlusion involving the intracranial internal carotid artery (ICA) and/or the proximal middle cerebral artery (MCA) (M1–M2 segments) and were successfully revascularized (post-Retriever/post-adjunctive TIMI 2–3 …