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Purpose: To date, endovascular devices designed to treat ischemic stroke by recanalizing occluded vessels have been experimentally evaluated in the extracranial vasculature. The purpose of this project is to evaluate mechanical recanalization in a canine stroke model.
Materials and Methods: An autologous clot measuring between 2.4 mm in diameter and 1.5 cm in length was injected into the internal carotid artery (ICA) of eight adult mongrel dogs. Imaging was performed on all animals, including catheter angiography and MRI (DWI, PWI, T2WI, MRA …