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016 Intraventricular tissue plasminogen activator for the prevention of vasospasm and hydrocephalus after aneurysmal subarachnoid hemorrhage
  1. R Ramakrishna,
  2. L Sekhar,
  3. D Ramanathan,
  4. N Temkin,
  5. D Hallam,
  6. B Ghodke,
  7. L Kim
  1. Neurosurgery, University of Washington, Seattle, Washington, USA

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Introduction: Among the sequelae of aneurysmal SAH are vasospasm and hydrocephalus. This study aims to assess whether intraventricular tissue plasminogen activator (tPA) results in fewer angioplasties and/or CSF shunting procedures.

Methods: 41 patients (group A, Hunt and Hess (HH) 3–5) from 2007 to 2008 received intraventricular tPA and lumbar drainage for a minimum of 5 days (range 5–7 days) and were compared …

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