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Original research
The Neuroform Atlas stent to assist coil embolization of intracranial aneurysms: a multicentre experience
  1. Christian Ulfert1,
  2. Mirko Pham2,
  3. Michael Sonnberger3,
  4. Franco Amaya2,
  5. Johannes Trenkler3,
  6. Martin Bendszus1,
  7. Markus A Möhlenbruch1
  1. 1 Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany
  2. 2 Institute for Diagnostic and Interventional Neuroradiology, University Hospital Würzburg, Würzburg, Germany
  3. 3 Institute of Neuroradiology, Kepler University Hospital, Linz, Austria
  1. Correspondence to Dr Markus A Möhlenbruch, Department of Neuroradiology, Heidelberg University Hospital, Heidelberg 69120, Germany; markus.moehlenbruch{at}


Objective To assess the clinical safety and efficacy of the Atlas microstent in stent-assisted coil embolization of wide-necked intracranial aneurysms.

Methods Single-center observational study in 36 patients (24 female, 12 male, mean age 56 years) with 37 aneurysms for the endovascular treatment of wide-necked aneurysms. After giving informed consent, patients were included according to the following criteria: aneurysm dome-to-neck ratio <2 or neck diameter >4 mm, and a parent vessel diameter of ≤4.5 mm. Primary endpoint for clinical safety was absence of death, absence of major or minor stroke, and absence of transient ischemic attack. Primary endpoint for treatment efficacy was complete angiographic occlusion according to the Raymond-Roy occlusion classification (RROC) immediately after the procedure.

Results In 36/37 (97%) cases, the primary endpoint of safety was reached, one patient had a transitory ischemic attack which completely resolved until discharge. In 31/37 (84%) cases, complete occlusion (RROC 1) was reached, and in 6/36 (17%), a residual neck remained (RROC 2). A sequential approach (first stent, then coiling through the same catheter) was used in 21 cases; the other 16 were treated with the jailing technique. Deployment was technically successful in all cases. Follow-up at a median of 6.1 months was available for 29/37 (78%) aneurysms and showed complete occlusion in 27/29 aneurysms (93%) and a neck remnant in 2 cases (7%).

Conclusion Deployment of the Neuroform Atlas microstent is a safe and effective method for the treatment of intracranial wide-necked aneurysms.

  • aneurysm
  • angiography
  • stent
  • coil

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  • Contributors Conception and design, CU and MAM. Data acquisition, all authors. Drafting the article, CU and MAM. Critically revising the article, all authors. Final approval of the version to be published, all authors. Agreement of accountability for all aspects of the work, all authors.

  • Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests MB has received honoraria or is consultant for Guerbet, Novartis, Codman, and Roche. MM has received honoraria or is consultant for Acandis, Codman, Microvention, and Phenox.

  • Patient consent Detail has been removed from this case description/these case descriptions to ensure anonymity. The editors and reviewers have seen the detailed information available and are satisfied that the information backs up the case the authors are making.

  • Ethics approval Local ethics committee.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Presented at Parts of the results have been presented at WFITN 2017 and Neurad 2017.