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Original research
A comparison between the new Low-profile Visualized Intraluminal Support (LVIS Blue) stent and the Flow Redirection Endoluminal Device (FRED) in bench-top and cadaver studies
  1. Yoshikazu Matsuda1,2,
  2. Joonho Chung1,3,
  3. Kiffon Keigher1,
  4. Demetrius Lopes1
  1. 1Department of Neurological Surgery, Rush University Medical Center, Chicago, Illinois, USA
  2. 2Department of Neurosurgery, Wakayama Medical University, Wakayama City, Japan
  3. 3Department of Neurosurgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
  1. Correspondence to Dr Demetrius K Lopes, Department of Neurological Surgery, Rush University Medical Center, 1725 W. Harrison St, Professional Building Suite 855, Chicago, IL 60612, USA; Demetrius_Lopes{at}


Object The aim of this study is to demonstrate the differences between the new Low-profile Visualized Intraluminal Support (LVIS Blue) stenting device and the Flow Redirection Endoluminal Device (FRED) using a series of bench-top evaluations and optical coherence tomography (OCT) images in a cadaveric preparation of the basilar artery.

Methods The first part of the evaluation was bench-top microscopic documentation of metal coverage for LVIS Blue and FRED stents. OCT images of the cerebral vessels and deployed stents were acquired using OCT intravascular imaging. The stents were deployed from the left posterior cerebral artery to the basilar artery in a fresh frozen cadaver. Wall apposition and the relationship to jailed perforators were evaluated.

Results The metal coverage along the inner curves of the LVIS Blue stent was similar to that along the outer curves of the FRED stent. The LVIS Blue stent cell size was compatible for crossing with the tested microcatheters after deployment of the stent. The LVIS Blue stent showed better wall apposition and less coverage of the perforator than the FRED stent in the cadaver experiment.

Conclusions LVIS Blue has a good crossing profile for microcatheters, better wall apposition, and less perforator coverage than FRED. These are desirable features in territories with high densities of perforators such as the posterior circulation.

  • Stent
  • Aneurysm

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  • Contributors DKL conceived the study. YM and JC executed the study. All authors reviewed the final version of the submitted manuscript.

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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