Background and purpose Flow diversion has emerged as a highly effective treatment for intracranial aneurysms. We assess the yield of further angiographic follow-up in aneurysms that have achieved adequate occlusion after treatment with the Pipeline Embolization Device (PED).
Methods This is a single institution, retrospective study. Inclusion criteria were as follows: 1) patients with one or more aneurysms treated with PED, 2) available short term (<12 months) follow-up digital subtraction angiography (DSA), 3) complete (100%) or near-complete (>95%) occlusion on short-term follow-up DSA, and 4) available further angiographic follow-up (DSA, MRA, or CTA).
Results A total of 146 patients were identified. Aneurysm size was 8.4±5.1 mm on average. Mean angiographic follow-up time was 29.7±12.2 months. On short-term follow-up DSA images, 132 (90.4%) had complete aneurysm occlusion and 14 (9.6%) had near-complete occlusion. Four patients (3%) had further DSA follow-up alone, 30 patients (21%) had further DSA and MRA/CTA follow-up, and 112 patients (76%) had further MRA/CTA follow-up alone. On further angiographic follow-up (DSA, MRA, and/or CTA), no patient had a decrease in the degree of aneurysm occlusion (recurrence) or required retreatment. Of the 14 patients with near-complete occlusion on initial DSA images, 7 patients (50%) progressed to complete aneurysm occlusion on further angiographic follow-up.
Conclusion This study did not find any diagnostic yield in repeating cerebral angiography in adequately occluded aneurysms with the PED. We do not recommend repeat angiographic follow-up once aneurysms have achieved complete occlusion with the PED unless clinically warranted.
Disclosures N. Chalouhi: None. P. Patel: None. E. Atallah: None. A. Chitale: None. M. Lang: None. S. Tjoumakaris: None. D. Hasan: None. M. Smith: None. R. Rosenwasser: None. P. Jabbour: None.
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.