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E-147 A retrospective review of the impact of aspirin use in subarachnoid hemorrhage
  1. V Patel1,
  2. F Al Mufti1,
  3. R Gupta2
  1. 1Neurosurgery, Westchester Medical Center, Valhalla, NY
  2. 2Neurosurgery, Rutgers New Jersey Medical School, Newark, NJ


Objective There is limited evidence on the use of aspirin (ASA) to reduce the risk and morbidity of cerebral aneurysmal rupture. This analysis retrospectively assessed aspirin use in patients presenting to our institution with aneurysm rupture.

Methods We evaluated 7 years of retrospective data from our neurovascular center and an existing database of patients with aneurysmal rupture. Initial presentation, hospital course and discharge outcomes were evaluated and compared based on whether or not patients were on ASA at the time of aneurysm rupture.

Results A total of 18 cases with patients on ASA and 168 control patients were identified. ASA use did not appear to lead to differences in initial presentation, including Hunt-Hess score and Fisher grade. In addition, ASA use was not associated with increased rates of delayed cerebral ischemia (DCI) or worsened modified Rankin score (mRs) at 90 days. Our analysis showed that increased Hunt Hess score and the presence of DCI are both associated with increased mRS at 90 days.

Conclusions Use of ASA does not appear to confer worse outcomes in cerebral aneurysm rupture and subarachnoid hemorrhage.

Disclosures V. Patel: None. F. Al Mufti: None. R. Gupta: None.

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