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E-079 Time of day and endovascular treatment decision in acute stroke – insights from an international multidisciplinary survey
  1. N Kashani1,
  2. J Ospel2,
  3. A Wilson1,
  4. W Kunz3,
  5. P Sylaia4,
  6. B Baxter5,
  7. B Campbell6,
  8. U Fischer7,
  9. A Rabinstein8,
  10. S Yoshimura9,
  11. J Heo10,
  12. B Kim11,
  13. M Cherian12,
  14. F Turjman13,
  15. M Foss1,
  16. B Menon1,
  17. G Saposnik14,
  18. M Goyal1
  1. 1Radiology, University of Calgary, Calgary, AB, Canada
  2. 2Radiology, University Hospital Basel, Basel, Switzerland
  3. 3Radiology, University Hospital Munich, Munich, GERMANY
  4. 4Radiology, University of Calgary, Thiruvananthapuram, India
  5. 5Radiology, Erlanger Hospital Chattanooga, Chattanooga, TN
  6. 6Radiology, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia
  7. 7Radiology, University Hospital Bern (Inselspital), Bern, Switzerland
  8. 8Radiology, Mayo Clinic Rochester, Calgary, MN
  9. 9Radiology, University of Calgary, Hyogo, Japan
  10. 10Neurology, Yonsei University, Seoul, Korea, republic of
  11. 11Radiology, St. Mary’s Hospital Seoul, Calgary, Korea, republic of
  12. 12Radiology, University of Calgary, Tamil Nadu, India
  13. 13Radiology, Centre Hospitalier Universitaire de Lyon, Lyon, France
  14. 14Radiology, University of Toronto, Calgary, ON, Canada


Background The decision to proceed with endovascular thrombectomy should ideally be made independent of inconvenience factors such as daytime, especially in cases supported by level IA evidence. The treatment decision may be influenced by the time of day when facing level 2B evidence cases. We assessed the influence of patient presentation time on EVT decision-making under current local resources and assumed ideal conditions.

Methods In an international cross-sectional survey among 607 stroke physicians, participants were asked to give their treatment decisions to 10 out of 22 randomly assigned case scenarios, 8 of them were level 1A evidence cases (all daytime scenarios), 11 were scenarios where level 2B evidence supports EVT, among them 7 daytime scenarios (8:00 am- 5:00 pm) and 4 overnight cases (10 pm:00 - 7:00 am). The remaining 3 (2 daytime and 1 nighttime) cases were not covered by current treatment guidelines. Participants stated A) their treatment approach assuming there were no practice constraints, and B) the treatment they would pursue under their current local resources. Endovascular treatment decision in level 2B scenarios was analyzed with regard to presentation time.

Results 3034 responses for 12 case scenarios from 607 physicians from 38 countries with level 2B evidence and 2208 for level 1A evidence for EVT were received. In the subgroup of level 2B evidence scenarios, participants selected EVT more often in the overnight cases (in 74.2% under assumed ideal conditions and in 70.7% under current local resources) than in the daytime scenarios (in 67.2% and 63.8% respectively). Overnight presentation did not increase the risk for a treatment decision against EVT. Current nighttime EVT decision rates for level 2B scenarios in 7 countries were > 10% lower than ideal nighttime EVT decision rates.

Conclusion Overall, overnight presentation did not increase the risk of a treatment decision against EVT when facing level 2B evidence. Hence, presentation time is unlikely to influence endovascular treatment decision-making in this subset of stroke patients. Current nighttime EVT decision rates in 7 countries were substantially lower than ideal nighttime EVT rates, potentially indicating limited access to endovascular treatment beyond working hours.

Disclosures N. Kashani: None. J. Ospel: None. A. Wilson: None. W. Kunz: None. P. Sylaia: None. B. Baxter: None. B. Campbell: None. U. Fischer: None. A. Rabinstein: None. S. Yoshimura: None. J. Heo: None. B. Kim: None. M. Cherian: None. F. Turjman: None. M. Foss: None. B. Menon:None. G. Saposnik: None. M. Goyal: None.

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