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Research and neurointerventional surgery: a roadmap of federal funding opportunities
  1. William J Mack
  1. Neurosurgery, University of Southern California, Los Angeles, California, USA
  1. Correspondence to Dr William J Mack, Neurosurgery, University of Southern California, Los Angeles, CA 90007, USA; wjmack{at}

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Scientific research is critical to the field of neurointerventional surgery. An important step in building successful research programs is understanding the available funding opportunities. This column reviews relevant federal research funding mechanisms accessible to neurointerventional surgeons through the National Institutes of Health (NIH) at various career stages.


Federal funding at the resident/fellow level allows for protected time, mentorship, and early exposure to rigorous scientific methodology. These early funding mechanisms also enhance a trainee’s abilities to compete for career development/independent grant awards as a junior faculty member. The NIH/NINDS R25 Research Education Program supports residents and fellows in neurology, neurosurgery, neuropathology, and neuroradiology. This mechanism specifically caters to resident trainees preparing for careers in neurointerventional surgery as it serves all three subspecialties in this field. Established by the NINDS in 2009, the R25 mechanism is an institutional award that offers 12–18 months of grant funding for mentored research. The grantee is awarded funding during residency training at one of over 20 program sites that hold a parent grant award and they can renew/continue the funding as a resident or fellow.1 2 Many neurointerventional surgeons are past R25 grant awardees and a significant number of senior stroke neurologists, cerebrovascular surgeons, and neurointerventional surgeons are current principal investigators on institutional R25 awards. NIH/NINDS T-Series grants and F-Series fellowships provide individual research training opportunities to undergraduates, doctoral candidates, and postdoctoral scholars. T-Series grants are institutional (secured by senior investigators or institutions through a parent grant) and F-Series fellowships are individual (awarded directly to the postdoctoral trainee). Specifically, F32 awards provide mentored training to broaden a grantee’s scientific background and extend their potential for research. These grants are typically awarded for up to 3 years …

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  • Contributors WJM is the sole contributor.

  • Funding WJM is supported by the following federal grants, none of which are directly related to this manuscript: NIEHS R01ES024936, NINDS R21NS116720, NIA P01AG055367, NINDS R25NS099008.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Commissioned; internally peer reviewed.