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Original research
Trends in hospital procedure volumes for intra-arterial treatment of acute ischemic stroke: results from the paul coverdell national acute stroke program
  1. Ganesh Asaithambi1,
  2. Xin Tong2,
  3. Kamakshi Lakshminarayan3,
  4. Sallyann M Coleman King2,
  5. Mary G George2
  1. 1 United Hospital, St Paul, Minnesota, USA
  2. 2 Centers for Disease Control and Prevention, Atlanta, Georgia, USA
  3. 3 University of Minnesota Medical School Twin Cities, Minneapolis, Minnesota, USA
  1. Correspondence to Dr Ganesh Asaithambi, Neurology, United Hospital, St. Paul, MN 55102, USA; ganesh785{at}


Background Rates of intra-arterial revascularization treatments (IAT) for acute ischemic stroke (AIS) are increasing in the USA. Using a multi-state stroke registry, we studied the trend in IAT use among patients with AIS over a period spanning 11 years. We examined the impact of IAT rates on hospital procedure volumes and patient outcome after stroke.

Methods We used data from the Paul Coverdell National Acute Stroke Program (PCNASP) and explored trends in IAT between 2008 and 2018. Patient outcomes were examined by rates of IAT procedures across hospitals. Specifically, outcomes were compared across low-volume (<15 IAT per year), medium-volume (15–30 IAT per year), and high-volume hospitals (>30 IAT per year). Favorable outcome was defined as discharge to home.

Results There were 612 958 patients admitted with AIS to 687 participating hospitals within the PCNASP during this study. Only 2.9% of patients (mean age 68.5 years, 49.3% women) received IAT. The percent of patients with AIS receiving IAT increased from 1% in 2008 to 5.3% in 2018 (p<0.001). The proportion of low-volume hospitals decreased over time (p<0.001), and the proportions of medium-volume (p=0.007) and high-volume hospitals (p<0.001) increased between 2008 and 2018. When compared with medium-volume hospitals, high-volume hospitals had a higher (p<0.0001) and low-volume hospitals had a lower (p<0.0001) percent of patients discharged to home.

Conclusion High-volume hospitals were associated with a higher rate of favorable outcome. With the increased use of IAT among patients with AIS, the proportion of low-volume hospitals performing IAT significantly decreased.

  • stroke
  • intervention
  • thrombectomy

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  • Contributors GA: conception, study design, manuscript preparation. XT: conception, study design, data collection, manuscript preparation. KL: conception, manuscript preparation. SMCK: conception, manuscript preparation. MGG: conception, study design, data collection, manuscript preparation. Each author listed should receive authorship credit based on substantial contribution to the article, revision of the article, and final approval of the article for submission to this journal.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Disclaimer The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article or uploaded as supplementary information.