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  • Motor neuroprosthesis implanted with neurointerventional surgery improves capacity for activities of daily living tasks in severe paralysis: first in-human experience

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Motor neuroprosthesis implanted with neurointerventional surgery improves capacity for activities of daily living tasks in severe paralysis: first in-human experience

Authors

  • Thomas J Oxley Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia Synchron, Inc, Campbell, California, USA PubMed articlesGoogle scholar articles
  • Peter E Yoo Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia Synchron, Inc, Campbell, California, USA PubMed articlesGoogle scholar articles
  • Gil S Rind Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia Synchron, Inc, Campbell, California, USA PubMed articlesGoogle scholar articles
  • Stephen M Ronayne Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia Synchron, Inc, Campbell, California, USA PubMed articlesGoogle scholar articles
  • C M Sarah Lee Neurology, Calvary Health Care Bethlehem, South Caulfield, Victoria, Australia PubMed articlesGoogle scholar articles
  • Christin Bird Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Victoria Hampshire Synchron, Inc, Campbell, California, USA PubMed articlesGoogle scholar articles
  • Rahul P Sharma Interventional Cardiology, Cardiovascular Medicine Faculty, Stanford University, Stanford, California, USA PubMed articlesGoogle scholar articles
  • Andrew Morokoff Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia Neurosurgery, Melbourne Health, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • Daryl L Williams Anaesthesia, Melbourne Health, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • Christopher MacIsaac Intensive Care Unit, Melbourne Health, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • Mark E Howard Institute for Breathing and Sleep, Austin Health, Heidelberg, Victoria, Australia PubMed articlesGoogle scholar articles
  • Lou Irving Respiratory Medicine, Melbourne Health, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • Ivan Vrljic Radiology, Melbourne Health, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • Cameron Williams Radiology, Melbourne Health, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • Sam E John Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia Department of Biomedical Engineering, University of Melbourne, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Frank Weissenborn Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • Madeleine Dazenko Neurology, Calvary Health Care Bethlehem, South Caulfield, Victoria, Australia PubMed articlesGoogle scholar articles
  • Anna H Balabanski Neurology, Melbourne Health, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • David Friedenberg Battelle Memorial Institute, Columbus, Ohio, USA PubMed articlesGoogle scholar articles
  • Anthony N Burkitt Department of Biomedical Engineering, University of Melbourne, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Yan T Wong Department of Electrical and Computer Systems Engineering, Monash University, Clayton, Victoria, Australia PubMed articlesGoogle scholar articles
  • Katharine J Drummond Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia Neurosurgery, Melbourne Health, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • Patricia Desmond Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia Radiology, Melbourne Health, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • Douglas Weber Department of Mechanical Engineering and Neuroscience Institute, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Timothy Denison Synchron, Inc, Campbell, California, USA Institute of Biomedical Engineering, Oxford University, Oxford, Oxfordshire, UK PubMed articlesGoogle scholar articles
  • Leigh R Hochberg Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Harvard University, Cambridge, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Susan Mathers Neurology, Calvary Health Care Bethlehem, South Caulfield, Victoria, Australia PubMed articlesGoogle scholar articles
  • Terence J O'Brien Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia Neurology, Melbourne Health, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • Clive N May Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • J Mocco Neurosurgery, The Mount Sinai Health System, New York, New York, USA PubMed articlesGoogle scholar articles
  • David B Grayden Department of Biomedical Engineering, University of Melbourne, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Bruce C V Campbell Medicine, University of Melbourne, Parkville, Victoria, Australia Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Peter Mitchell Radiology, Melbourne Health, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • Nicholas L Opie Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia Synchron, Inc, Campbell, California, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Thomas J Oxley, Vascular Bionics Laboratory, Departments of Medicine, Neurology and Surgery, Melbourne Brain Centre at the Royal Melbourne Hospital, The University of Melbourne, Melbourne, VIC 3050, Australia; thomas.oxley{at}unimelb.edu.au
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Citation

Oxley TJ, Yoo PE, Rind GS, et al
Motor neuroprosthesis implanted with neurointerventional surgery improves capacity for activities of daily living tasks in severe paralysis: first in-human experience
Journal of NeuroInterventional Surgery 2021;13:102-108.

Publication history

  • Received September 11, 2020
  • Revised October 7, 2020
  • Accepted October 9, 2020
  • First published October 28, 2020.
Online issue publication 
January 26, 2021

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  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.