Article Text

Download PDFPDF
Original research
Sacroiliac joint injections with the guidance of three-dimensional cone beam computed tomography (3D-CBCT) and fluoroscopy fusion
  1. Nisa Cem Oren1,
  2. Saad Ali1,
  3. James Mok2,
  4. Zheng Feng Lu1,
  5. Seon-Kyu Lee3
  1. 1 Radiology, University of Chicago Medical Center, Chicago, Illinois, USA
  2. 2 Spine Surgery, DuPage Medical Group, Downers Grove, Illinois, USA
  3. 3 Radiology, Montefiore Hospital and Medical Center, Bronx, New York, USA
  1. Correspondence to Dr Seon-Kyu Lee, Radiology, Montefiore Hospital and Medical Center, Bronx, NY 10467-2401, USA; sklee{at}


Background We describe our diagnostic sacroiliac joint (SIJ) injection technique under the guidance of three-dimensional cone beam computed tomography (3D-CBCT) fused with real-time fluoroscopy.

Methods A retrospective review of 17 patients (mean age 55.4 (range 40–74) years) who received a total of 23 diagnostic SIJ injections between March 2016 and November 2017 were performed. Pre- and post-procedure pain scores were reviewed from the medical records and then these findings were correlated with which patients were and were not diagnosed with SIJ pain by clinical management. The final diagnosis of SIJ-related pain was made in cases with at least 50% symptomatic improvement following SIJ-specific pain treatments.

Results Some 87% (n=20/23) of injections achieved more than 50% pain relief after the diagnostic SIJ injection. The final diagnosis of the target SIJ-related pain after follow-up and management was found in 90% (n=18/20) of cases. There were two cases with positive tests diagnosed as non-SIJ pain including one with the diagnosis of femuroacetabular impingement and one with pain related to loosening of knee hardware. The sensitivity, specificity, positive predictive value, and negative predicative value of diagnostic SIJ injections were 100%, 60%, 89%, and 100%, respectively, with a 40% false-positive rate. There were no procedure-related complications.

Conclusion 3D-CBCT fused with real-time fluoroscopy for SIJ injection is accurate and safe.

  • CT
  • intervention
  • lumbosacral

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Contributors NCO and S-KL conceived the project idea; NCO collected and analyzed data; NCO drafted the manuscript; S-KL, SA, JM, and ZFL analyzed and reviewed the data and edited the manuscript; S-KL reviewed the data, edited the manuscript, and supervised the project. All the authors discussed the results and contributed to the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication The local institutional review board (IRB) exempted the researchers from obtaining informed consent from the enrolled patients.

  • Ethics approval All procedures performed in the study that involved human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by The University of Chicago Biological Sciences Division/University of Chicago Medical Center Institutional Review Board (IRB) (decision number IRB17-1638).

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article.