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Letter by Tang et al regarding the article ‘Leukoaraiosis and acute ischemic stroke: 90-day clinical outcome following endovascular recanalization, with proposed “L-ASPECTS”’
  1. Xiaojia Tang1,2,
  2. Yuhan Luo1,2,
  3. Peipei Liu2,3,
  4. Yingzhu Chen3
  1. 1 Neurology, Dalian Medical University, Dalian, Liaoning Province, China
  2. 2 Neurology, Yangzhou University Affiliated Northern Jiangsu People's Hospital, Yangzhou, Jiangsu Province, China
  3. 3 Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu Province, China
  1. Correspondence to Dr Peipei Liu; doclpp87{at}; Dr Yingzhu Chen; yzchendr{at}

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We read with great interest the article by Bandaru et al 1 in a recent issue of the Journal of NeuroInterventional Surgery in which they have identified that leukoaraiosis (LA) severity on pre-mechanical thrombectomy (MT) no contrast computed tomography (NCCT) is associated with worse 90-day outcomes in patients with acute ischemic stroke (AIS) following endovascular recanalization, and is an independent risk factor for worse outcomes. Moreover, they proposed a modification to the ASPECT score, L-ASPECTS, which combines ischemia with white matter injury on the basis of the original ASPECTS.2

In the latest BEST trial study,3 Mistry et al found that patients with moderate-to-severe LA had …

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  • All the authors contributed equally to this letter.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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