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Hafezi-Nejad et al have provided an overview of the United States’ national trends, regional variations, associated diagnoses, and outcomes from hospitalized patients treated with vertebroplasty and/or kyphoplasty between 2004 and 2017.1 While some results were predictable, such as decreased use following publication of negative augmentation trials, their review has also yielded other surprising and certainly intriguing results. It is important to consider, however, that this review is based on data obtained from the national inpatient sample. As such, the population analyzed would represent a group of patients with the most debilitating symptoms of vertebral compression fractures such as unremitting pain and immobility.
The authors describe a period of decreased use from 2008 to 2012 as being attributable to the 2009 publication of two contentious and negative trials comparing vertebroplasty non-operative …
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial, or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.