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Ischemic stroke
Original research
MRS SOFIA: a multicenter retrospective study for use of Sofia for revascularization of acute ischemic stroke
  1. Waleed Brinjikji1,
  2. Eytan Raz2,
  3. Reade De Leacy3,
  4. Dan Meila4,
  5. Maxim Mokin5,
  6. Edgar A Samaniego6,
  7. Maksim Shapiro7,
  8. Devin Bageac3,
  9. Alberto Varon6,
  10. Zeguang Ren5,
  11. Lorenzo Rinaldo8,
  12. Harry J Cloft9
  1. 1 Mayo Clinic Minnesota, Rochester, Minnesota, USA
  2. 2 Department of Radiology, NYU, New York, New York, USA
  3. 3 Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA
  4. 4 Department of Radiology and Neuroradiology, Klinikum Duisburg - Sana Kliniken, Duisburg, Germany
  5. 5 Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, Florida, USA
  6. 6 Interventional Neuroradiology/Endovascular Neurosurgery Division Department of Neurology, Neurosurgery and Radiology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
  7. 7 Department of Interventional Radiology, New York University Langone Medical Center, New York, New York, USA
  8. 8 Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA
  9. 9 Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA
  1. Correspondence to Dr Waleed Brinjikji, Mayo Clinic Minnesota, Rochester, Minnesota, USA; Brinjikji.Waleed{at}mayo.edu

Abstract

Background Over the past several years there has been increased interest in the use of the Sofia aspiration system (MicroVention, Tustin, California) as a primary aspiration catheter.

Objective To perform a multicenter retrospective study examining the efficacy of the Sofia aspiration catheter as a standalone aspiration treatment for large vessel occlusion.

Methods Consecutive cases in which the Sofia catheter was used for aspiration thrombectomy for large vessel occlusion were included. Exclusion criteria were the following: (1) Sofia not used for first pass, and (2) a stent retriever used as an adjunct on the first pass. The primary outcome of the study was first pass recanalization (Thrombolysis in Cerebral Infarction (TICI) 2c/3). Secondary outcomes included first pass TICI 2b/3, crossover to other thrombectomy devices, number of passes, time from puncture to recanalization, and complications.

Results 323 patients were included. First pass TICI 2c/3 was achieved in 49.8% of cases (161/323). First pass TICI 2b/3 was achieved in 69.7% (225/323) of cases. 74.8% had TICI 2b/3 with the Sofia alone. Crossover to other thrombectomy devices occurred in 29.1% of cases (94/323). The median number of passes was 1 (IQR=1–3). Median time from puncture to recanalization was 26 min (IQR=17–45). Procedure related complications occurred in 3.1% (10/323) of cases.

Conclusion Our study highlights the potential advantage of the Sofia aspiration catheter for primary aspiration thrombectomy in acute ischemic stroke. High rates of first pass recanalization with low crossover rates to other thrombectomy devices were achieved. Median procedure time was low, as were procedural complications.

  • stroke
  • thrombectomy

Data availability statement

No data are available.

https://doi.org/10.1136/neurintsurg-2020-017042

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    Data availability statement

    No data are available.

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    Footnotes

    • Twitter @wbrinjikji, @rdeleacymd

    • Contributors All authors contributed to data collection and analysis. All authors made critical revisions to the manuscript. All authors contributed to study design. WB drafted the original manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests WB is a consultant and proctor for MicroVention. Money paid to institution <$10 000.

    • Provenance and peer review Not commissioned; externally peer reviewed.