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Response to letter: How much will a catheter tip expand in aspiration thrombectomy?
  1. Jiahui Li1,2,
  2. Oscar Castaño3,4,
  3. Marc Ribo2,5
  1. 1 Stroke Research, Vall d'Hebron Research Institute, Barcelona, Barcelona, Spain
  2. 2 Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain
  3. 3 Electronics and Biomedical Engineering, University of Barcelona, Barcelona, Catalunya, Spain
  4. 4 Biomaterials for Regenerative Therapies, Institute for Bioengineering in Catalonia, Barcelona, Catalunya, Spain
  5. 5 Stroke Unit, Neurology, Hospital Vall d'Hebron, Barcelona, Spain
  1. Correspondence to Dr Marc Ribo, Stroke Unit. Neurology, Hospital Vall d'Hebron, Barcelona 119-129, Spain; marcriboj{at}

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We thank Liu and Kallmes for their interest and valuable observations, which might help to improve the understanding of our study.1

Our findings show, in all catheters, an increased aspiration effective force as compared with the expected theoretical force corresponding to the labeled catheter diameter.2 This is an objective and evidenced finding.

We agree with Liu and Kallmes that the reasons for these differences are probably basically due to two different factors:

  • Catheter tip distensibility

  • Clot–catheter friction.

The proportional impact of each factor might certainly be discussed. Both causes are also correlated, because a higher distensibility leads to a larger clot–catheter interaction surface. In our study, after adjusting for tip distensibility, an almost straight correlation is found between the measured force and the effective inner diameter (ID) for all catheters. This is very revealing and hard to believe that it is a coincidence if friction forces exert a higher effect.

Liu and Kallmes point out several flaws that …

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  • Contributors All authors contributed equally to this work.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.

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