Article Text

Download PDFPDF
Original research
Chronic headaches and middle meningeal artery embolization
  1. Joshua S Catapano,
  2. Katherine Karahalios,
  3. Visish M Srinivasan,
  4. Jacob F Baranoski,
  5. Caleb Rutledge,
  6. Tyler S Cole,
  7. Andrew F Ducruet,
  8. Felipe C Albuquerque,
  9. Ashutosh P Jadhav
  1. Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA
  1. Correspondence to Dr Ashutosh P Jadhav, Neurology, Barrow Neurological Institute, Phoenix, Arizona, USA; neuropub{at}


Background The middle meningeal artery (MMA) has been implicated in chronic headaches, but no studies have examined the relationship between MMA embolization and headaches.

Methods Patients treated with MMA embolization for a chronic subdural hematoma (cSDH) between January 1, 2018, and December 31, 2020, were retrospectively assessed. Patients with a Glasgow Coma Scale (GCS) score of 15 at discharge received a follow-up telephone call to assess their history of chronic headache, defined as a headache ≥2 years before the cSDH and symptoms ≥2 days/month. A Headache Impact Test (HIT-6) was performed during the follow-up telephone call. The primary outcome was resolution or improvement of headaches after embolization.

Results Of 76 patients undergoing MMA embolization for a cSDH during the study period, 56 (74%) had a discharge GCS score of 15. Of these 56 patients, 46 (82%) responded to a follow-up telephone call and were analyzed (mean [SD] age 68 [11] years; 36 [78%] men and 10 [22%] women). Nine (20%) reported chronic headaches before embolization. With a mean (SD) follow-up of 489 (173) days, eight of the nine patients reported improvement of chronic headaches, with seven having complete resolution. For these nine patients, the mean (SD) HIT-6 score was significantly higher before embolization than after embolization (64 [7.1] vs 40 [9.1], p<0.001).

Conclusion In patients with chronic headaches who underwent MMA embolization for a cSDH, the majority reported improvement of headaches after the procedure. Future prospective studies are warranted to assess the usefulness of MMA embolization to treat chronic headaches.

  • angiography
  • subdural

Data availability statement

No data are available.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Data availability statement

No data are available.

View Full Text


  • Twitter @ashupjadhav

  • Contributors JSC: Concept, manuscript writing, statistical analysis. KK: Data collection. VMS: Manuscript editing. JFB: Data collection, manuscript editing. CR: Manuscript editing. TSC: Statistical analysis. AFD: Manuscript editing. FCA: Manuscript editing. APJ: Concept, editing and final approval of manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests AFD, FCA, and APJ serve on the editorial board of Journal of NeuroInterventional Surgery.

  • Provenance and peer review Not commissioned; internally peer reviewed.